Paradoxical high signal intensity of hepatocellular carcinoma in the hepatobiliary phase of Gd-EOB-DTPA enhanced MRI: initial experience
DC Field | Value | Language |
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dc.contributor.author | Lee, Seun Ah | - |
dc.contributor.author | Lee, Chang Hee | - |
dc.contributor.author | Jung, Woon Yong | - |
dc.contributor.author | Lee, Jongmee | - |
dc.contributor.author | Choi, Jae Woong | - |
dc.contributor.author | Kim, Kyeong Ah | - |
dc.contributor.author | Park, Cheol Min | - |
dc.date.available | 2020-11-03T03:50:40Z | - |
dc.date.issued | 2011-01 | - |
dc.identifier.issn | 0730-725X | - |
dc.identifier.issn | 1873-5894 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/13809 | - |
dc.description.abstract | Purpose: To describe the paradoxical high signal intensity of hepatocellular carcinoma (HCC) in the hepatobiliary phase on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI). Materials and Methods: A database search was performed to identify cases of HCC that showed unusual prolonged enhancement in the hepatobiliary phase of Gd-EOB-DTPA MRI. All patients received 3.0-T liver MRI including precontrast T1-weighted images, T2-weighted images and a post Gd-EOB-DTPA-enhanced dynamic study. The signal intensity of HCC was measured at pre-enhanced, arterial, portal, delayed and hepatobiliary phase using regions of interest. Radiologic and pathologic correlation was performed for the paradoxically prolonged enhancing portion of HCC in the hepatobiliary phase. Results: Four patients (all male, age range 44-70; mean 57.5 years) were included in this study. All patients showed HCC lesions that were low signal intensity (SI) on T1-WI, high SI on T2-WI, enhanced in arterial phase, and washed-out in delayed phase. All cases showed paradoxically high SI in hepatobiliary phase, which was unusual for HCC. Pathologically, they were all diagnosed as well-differentiated HCC with prominent cytoplasm and a bile secreting appearance. Conclusion: HCC may demonstrate the prolonged high signal intensity at the hepatobiliary phase on Gd-EOB-DTPA enhanced MRI. These HCCs tended to be highly differentiated and to have prominent bile secretion. Crown Copyright (C) 2011 Published by Elsevier Inc. All rights reserved. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Paradoxical high signal intensity of hepatocellular carcinoma in the hepatobiliary phase of Gd-EOB-DTPA enhanced MRI: initial experience | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1016/j.mri.2010.07.019 | - |
dc.identifier.scopusid | 2-s2.0-78649957927 | - |
dc.identifier.wosid | 000285570100011 | - |
dc.identifier.bibliographicCitation | MAGNETIC RESONANCE IMAGING, v.29, no.1, pp 83 - 90 | - |
dc.citation.title | MAGNETIC RESONANCE IMAGING | - |
dc.citation.volume | 29 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 83 | - |
dc.citation.endPage | 90 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | FOCAL LIVER-LESIONS | - |
dc.subject.keywordPlus | HISTOPATHOLOGIC FINDINGS | - |
dc.subject.keywordPlus | SPIRAL CT | - |
dc.subject.keywordPlus | TRANSPORT | - |
dc.subject.keywordPlus | TUMORS | - |
dc.subject.keywordAuthor | Gadoxetic acid | - |
dc.subject.keywordAuthor | Gd-EOB-DTPA | - |
dc.subject.keywordAuthor | Green hepatoma | - |
dc.subject.keywordAuthor | Hepatocellular carcinoma | - |
dc.subject.keywordAuthor | Liver | - |
dc.subject.keywordAuthor | MRI | - |
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