Relationship between the serum CA-125 level and bone mineral density in healthy pre- and post-menopausal women
DC Field | Value | Language |
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dc.contributor.author | Ahn, Ki Hoon | - |
dc.contributor.author | Park, Hyun Tae | - |
dc.contributor.author | Kim, Tak | - |
dc.contributor.author | Hur, Jun Young | - |
dc.contributor.author | Kim, Young Tae | - |
dc.contributor.author | Lee, Kyu Wan | - |
dc.contributor.author | Kim, Sun Haeng | - |
dc.date.available | 2020-11-03T05:48:20Z | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 0004-8666 | - |
dc.identifier.issn | 1479-828X | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14664 | - |
dc.description.abstract | Background: Osteoporosis and tumour-associated antigen (TAA) levels are associated with inflammatory processes, but little remains known about TAA levels and bone mineral density (BMD). Aims: We determined whether or not high-normal TAA levels are associated with a lower BMD in healthy women. Methods: A total of 3769 healthy women were enrolled from the health screening programme over 5 years. Each participant had undergone a basic health examination. Serum carbohydrate antigen (CA)-125, CA-19-9, carcinoembryonic antigen (CEA) and alpha-fetoprotein levels were evaluated as tumour markers. The correlations between serum TAA levels and BMD were analysed. Results: Carbohydrate antigen 125 and CEA levels were positively associated with a higher BMD in the pre-menopause. In the post-menopause, the CA-125 level was positively associated with BMD. In the pre-menopause, CA-125 (r = 0.102; P < 0.001) and CEA levels (r = 0.134; P < 0.001) had a significant correlation with BMD. In the post-menopause, CA-125 was negatively associated with alkaline phosphatase (r = -0.298; P < 0.001). Conclusions: There was a significant positive association between CA-125 and BMD in healthy women. Additional basic and clinical studies on the relationship between CA-125 and bone are needed. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY | - |
dc.title | Relationship between the serum CA-125 level and bone mineral density in healthy pre- and post-menopausal women | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1111/j.1479-828X.2010.01183.x | - |
dc.identifier.scopusid | 2-s2.0-77955733196 | - |
dc.identifier.wosid | 000280970400010 | - |
dc.identifier.bibliographicCitation | AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, v.50, no.4, pp 371 - 377 | - |
dc.citation.title | AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY | - |
dc.citation.volume | 50 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 371 | - |
dc.citation.endPage | 377 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.subject.keywordPlus | HORMONE REPLACEMENT THERAPY | - |
dc.subject.keywordPlus | C-REACTIVE PROTEIN | - |
dc.subject.keywordPlus | CARCINOEMBRYONIC ANTIGEN | - |
dc.subject.keywordPlus | TUMOR-MARKERS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordAuthor | bone mineral density | - |
dc.subject.keywordAuthor | carbohydrate antigen-125 | - |
dc.subject.keywordAuthor | pre- and post-menopausal women | - |
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