Pharmacologic treatment of acute kidney injury: Why drugs haven't worked and what is on the horizon
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jo S.K. | - |
dc.contributor.author | Rosner M.H. | - |
dc.contributor.author | Okusa M.D. | - |
dc.date.available | 2020-11-03T13:44:11Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1555-9041 | - |
dc.identifier.issn | 1555-905X | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/18418 | - |
dc.description.abstract | Current strategies to limit the extent of injury in acute renal failure are based on extensive studies that identified cellular and molecular mechanisms of acute kidney injury. Despite successes in various animal models, translation to human studies has failed or studies are inconclusive. This review describes past failures and barriers to successful clinical trials. It also focuses on promising preclinical studies using novel compounds that currently are in or close to human investigation. Implementation of previous or novel compounds in well-designed clinical trials provides hope for the successful treatment of this devastating disorder. Copyright © 2007 by the American Society of Nephrology. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.title | Pharmacologic treatment of acute kidney injury: Why drugs haven't worked and what is on the horizon | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.2215/CJN.03280906 | - |
dc.identifier.scopusid | 2-s2.0-34548438633 | - |
dc.identifier.bibliographicCitation | Clinical Journal of the American Society of Nephrology, v.2, no.2, pp 356 - 365 | - |
dc.citation.title | Clinical Journal of the American Society of Nephrology | - |
dc.citation.volume | 2 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 356 | - |
dc.citation.endPage | 365 | - |
dc.type.docType | Short Survey | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | acute kidney failure | - |
dc.subject.keywordPlus | clinical trial | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | review | - |
dc.subject.keywordPlus | treatment failure | - |
dc.subject.keywordPlus | Clinical Trials | - |
dc.subject.keywordPlus | Humans | - |
dc.subject.keywordPlus | Kidney Failure, Acute | - |
dc.subject.keywordPlus | Treatment Failure | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.