Detailed Information

Cited 0 time in webofscience Cited 18 time in scopus
Metadata Downloads

Comparison of the effectiveness of quadruple salvage regimen for Helicobacter pylori infection according to the duration of treatment

Full metadata record
DC Field Value Language
dc.contributor.authorChoung R.S.-
dc.contributor.authorLee S.W.-
dc.contributor.authorJung S.W.-
dc.contributor.authorHan W.S.-
dc.contributor.authorKim M.J.-
dc.contributor.authorJeen Y.T.-
dc.contributor.authorPark J.J.-
dc.contributor.authorLee H.S.-
dc.contributor.authorChun H.J.-
dc.contributor.authorUm S.H.-
dc.contributor.authorChoi J.H.-
dc.contributor.authorKim C.D.-
dc.contributor.authorRyu H.S.-
dc.contributor.authorHyun J.H.-
dc.date.available2020-11-03T14:50:38Z-
dc.date.issued2006-02-
dc.identifier.issn1598-9992-
dc.identifier.issn2233-6869-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/19255-
dc.description.abstractBACKGROUND/AIMS: At present, triple therapy schemes are recommended by national and international consensus conferences for the treatment of Helicobacter pylori (H. pylori) infection. However, even with the most effective current treatment regimens, about 10-20% of patients fail to eradicate H. pylori, necessitating alternative strategy to eradicate H. pylori in primary treatment failure. Therefore, we performed this study to evaluate the efficacy of quadruple therapy and to compare 1 and 2-week quadruple regimen as a second-line therapy. METHODS: The hospital records of 155 patients who failed to the standard triple therapy (proton pump inhibitor, amoxicillin, clarithromycin) were reviewed retrospectively, and divided the 1 or 2 weeks OBMT regimen (omeprazole 20 mg bid, bismuth salt 120 mg qid, metronidazole 500 mg tid, tetracycline 500 mg qid). Presence of H. pylori infection and side-effects of the treatment regimen were assessed 4 weeks after the cessation of treatment. RESULTS: One hundred and eight male and 47 female (mean age, 52.2+/-15.4) patients were enrolled. The overall eradication rate of H. pylori with quadruple therapy was 83.9% and the eradication rate was similar between 1 and 2 weeks of OBMT regimen (76.8% in OBMT 1 week, 87.9% in OBMT 2 weeks, respectively p=0.110). CONCLUSIONS: Quadruple therapy is an effective salvage regimen for H. pylori eradication after the failure of standard triple therapy. One week quadruple therapy is not significantly different from 2-weeks regimen as the second-line option for H. pylori eradication.-
dc.format.extent5-
dc.language한국어-
dc.language.isoKOR-
dc.titleComparison of the effectiveness of quadruple salvage regimen for Helicobacter pylori infection according to the duration of treatment-
dc.typeArticle-
dc.publisher.location대한민국-
dc.identifier.scopusid2-s2.0-33749162547-
dc.identifier.bibliographicCitationThe Korean journal of gastroenterology, v.47, no.2, pp 131 - 135-
dc.citation.titleThe Korean journal of gastroenterology-
dc.citation.volume47-
dc.citation.number2-
dc.citation.startPage131-
dc.citation.endPage135-
dc.type.docTypeArticle-
dc.identifier.kciidART001112798-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.subject.keywordPlusantiinfective agent-
dc.subject.keywordPlusantiulcer agent-
dc.subject.keywordPlusproton pump-
dc.subject.keywordPlusadult-
dc.subject.keywordPlusaged-
dc.subject.keywordPlusarticle-
dc.subject.keywordPluscomparative study-
dc.subject.keywordPlusdrug administration-
dc.subject.keywordPlusdrug antagonism-
dc.subject.keywordPlusdrug combination-
dc.subject.keywordPlusfemale-
dc.subject.keywordPlusHelicobacter infection-
dc.subject.keywordPlusHelicobacter pylori-
dc.subject.keywordPlushuman-
dc.subject.keywordPlusmale-
dc.subject.keywordPlusmiddle aged-
dc.subject.keywordPlusAdult-
dc.subject.keywordPlusAged-
dc.subject.keywordPlusAnti-Bacterial Agents-
dc.subject.keywordPlusAnti-Ulcer Agents-
dc.subject.keywordPlusDrug Administration Schedule-
dc.subject.keywordPlusDrug Therapy, Combination-
dc.subject.keywordPlusFemale-
dc.subject.keywordPlusHelicobacter Infections-
dc.subject.keywordPlusHelicobacter pylori-
dc.subject.keywordPlusHumans-
dc.subject.keywordPlusMale-
dc.subject.keywordPlusMiddle Aged-
dc.subject.keywordPlusProton Pumps-
dc.subject.keywordAuthorHelicobacter pylori-
dc.subject.keywordAuthorSecond-line quadruple therapy-
dc.subject.keywordAuthorDuration of treatment-
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Internal Medicine > 1. Journal Articles
5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Jung, Sung Woo photo

Jung, Sung Woo
Ansan Hospital (Department of Gastroenterology and Hepatology, Ansan Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE