Characterization and expression of a presomitic mesoderm-specific mespo gene in zebrafish
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yoo K.-W. | - |
dc.contributor.author | Kim C.-H. | - |
dc.contributor.author | Park H.-C. | - |
dc.contributor.author | Kim S.-H. | - |
dc.contributor.author | Kim H.-S. | - |
dc.contributor.author | Hong S.-K. | - |
dc.contributor.author | Han S. | - |
dc.contributor.author | Rhee M. | - |
dc.contributor.author | Huh T.-L. | - |
dc.date.available | 2020-11-03T19:46:08Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0949-944X | - |
dc.identifier.issn | 1432-041X | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/21517 | - |
dc.description.abstract | A complete zebrafish mespo cDNA encoding a protein of 131 amino acids with a bHLH domain in the C-terminal has been isolated. The bHLH domain of zebrafish Mespo is highly similar to those in the mouse, chick and Xenopus, sharing 82.4%, 80.4% and 74.5% amino acid identity, respectively. At 50% epiboly, the zebrafish mespo is first detected in the marginal zone of the blastoderm but excluding the prospective shield. Subsequently, mespo expression is intensified in the involuting mesoderm at 60% epiboly, and then restricted to the presomitic mesoderm (PSM) at 95% epiboly. At the 1-somite stage, mespo expression becomes reduced in the most rostral PSM. During segmentation, mespo expression is gradually downregulated at the most rostral segmental plate where cells are being coalesced to form somites. In spadetail mutant embryos, most of mespo-expressing cells were missing. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.title | Characterization and expression of a presomitic mesoderm-specific mespo gene in zebrafish | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.scopusid | 2-s2.0-0037837338 | - |
dc.identifier.bibliographicCitation | Development Genes and Evolution, v.213, no.4, pp 203 - 206 | - |
dc.citation.title | Development Genes and Evolution | - |
dc.citation.volume | 213 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 203 | - |
dc.citation.endPage | 206 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | complementary DNA | - |
dc.subject.keywordPlus | helix loop helix protein | - |
dc.subject.keywordPlus | protein mespo | - |
dc.subject.keywordPlus | transcription factor | - |
dc.subject.keywordPlus | unclassified drug | - |
dc.subject.keywordPlus | amino acid sequence | - |
dc.subject.keywordPlus | article | - |
dc.subject.keywordPlus | blastoderm | - |
dc.subject.keywordPlus | carboxy terminal sequence | - |
dc.subject.keywordPlus | chicken | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | DNA isolation | - |
dc.subject.keywordPlus | down regulation | - |
dc.subject.keywordPlus | embryo | - |
dc.subject.keywordPlus | embryo development | - |
dc.subject.keywordPlus | gene expression | - |
dc.subject.keywordPlus | gene mutation | - |
dc.subject.keywordPlus | genetic analysis | - |
dc.subject.keywordPlus | genetic code | - |
dc.subject.keywordPlus | involution | - |
dc.subject.keywordPlus | mesoderm | - |
dc.subject.keywordPlus | mouse | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | nucleotide sequence | - |
dc.subject.keywordPlus | priority journal | - |
dc.subject.keywordPlus | protein domain | - |
dc.subject.keywordPlus | sequence homology | - |
dc.subject.keywordPlus | somite | - |
dc.subject.keywordPlus | Xenopus | - |
dc.subject.keywordPlus | zebra fish | - |
dc.subject.keywordPlus | Amino Acid Sequence | - |
dc.subject.keywordPlus | Animals | - |
dc.subject.keywordPlus | Basic Helix-Loop-Helix Transcription Factors | - |
dc.subject.keywordPlus | Embryo, Nonmammalian | - |
dc.subject.keywordPlus | Extremities | - |
dc.subject.keywordPlus | Gene Expression Regulation, Developmental | - |
dc.subject.keywordPlus | Helix-Loop-Helix Motifs | - |
dc.subject.keywordPlus | Mesoderm | - |
dc.subject.keywordPlus | Molecular Sequence Data | - |
dc.subject.keywordPlus | Mutation | - |
dc.subject.keywordPlus | Sequence Homology, Amino Acid | - |
dc.subject.keywordPlus | T-Box Domain Proteins | - |
dc.subject.keywordPlus | Trans-Activators | - |
dc.subject.keywordPlus | Transcription Factors | - |
dc.subject.keywordPlus | Xenopus Proteins | - |
dc.subject.keywordPlus | Zebrafish | - |
dc.subject.keywordPlus | Zebrafish Proteins | - |
dc.subject.keywordPlus | Danio rerio | - |
dc.subject.keywordPlus | Eukaryota | - |
dc.subject.keywordPlus | Gallus gallus | - |
dc.subject.keywordPlus | Vertebrata | - |
dc.subject.keywordAuthor | bHLH | - |
dc.subject.keywordAuthor | Mespo | - |
dc.subject.keywordAuthor | Presomitic mesoderm | - |
dc.subject.keywordAuthor | Spadetail | - |
dc.subject.keywordAuthor | Zebrafish | - |
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