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Increased liver stiffness in extrahepatic cholestasis caused by choledocholithiasis

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dc.contributor.authorTrifan A.-
dc.contributor.authorSfarti C.-
dc.contributor.authorCojocariu C.-
dc.contributor.authorDimache M.-
dc.contributor.authorCretu M.-
dc.contributor.authorHutanasu C.-
dc.contributor.authorStanciu C.-
dc.contributor.authorSeo Y.S.-
dc.date.available2020-11-10T12:48:05Z-
dc.date.issued2011-
dc.identifier.issn1735-143X-
dc.identifier.issn1735-3408-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/31000-
dc.description.abstractBackground: Extrahepatic cholestasis that is caused by benign and malignant diseases has been reported to increase liver stifness (LS), as measured by transient elastogra-phy (TE).Objectives: The aim of this study was to evaluate LS in patients with extrahepatic cholestasis due to choledocholithiasis before and after endoscopic sphincterotomy and stone removal.Patients and Methods: LS was measured by TE (Fibroscan) in patients with extrahepatic cholestasis that was caused by choledocholithiasis before and 1 month after endoscopic sphincterotomy and successful stone removal.Results: We studied 12 patients (7 females, 5 males), aged 36 to 76 years (mean age 57.1 ± 11.6 years), with extrahepatic cholestasis that was caused by choledocholithiasis. LS was increased in all patients (range: 6.2-18.4 kPa; mean: 8.9 ± 3.5 kPa) before endoscopic therapy. Successful biliary drainage was efected by sphincterotomy and stone removal in all patients, which led to a signifcant decline in LS to 3.9-8.1 kPa (Mean: 5.6 ± 1.2 kPa; p < 0.001) within a mean observation time of 29 days. The decrease in LS values correlated signifcantly with a decline in serum total bilirubin levels (r = 0.691; p < 0.0001).Conclusions: Extrahepatic cholestasis due to choledocholithiasis increases LS and should be excluded before assesing liver fbrosis by transient elastography © 2011, BRCGL, Published by Kowsar M.P.Co All right reserved.-
dc.format.extent4-
dc.language영어-
dc.language.isoENG-
dc.titleIncreased liver stiffness in extrahepatic cholestasis caused by choledocholithiasis-
dc.typeArticle-
dc.publisher.location네델란드-
dc.identifier.scopusid2-s2.0-79957647892-
dc.identifier.bibliographicCitationHepatitis Monthly, v.11, no.5, pp 372 - 375-
dc.citation.titleHepatitis Monthly-
dc.citation.volume11-
dc.citation.number5-
dc.citation.startPage372-
dc.citation.endPage375-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordPlusbilirubin-
dc.subject.keywordPlusadult-
dc.subject.keywordPlusaged-
dc.subject.keywordPlusarticle-
dc.subject.keywordPlusbiliary tract drainage-
dc.subject.keywordPlusbiliary tract surgery-
dc.subject.keywordPlusbilirubin blood level-
dc.subject.keywordPlusclinical article-
dc.subject.keywordPluscommon bile duct stone-
dc.subject.keywordPluscontrolled study-
dc.subject.keywordPlusdigestive tract parameters-
dc.subject.keywordPluselastography-
dc.subject.keywordPlusendoscopic sphincterotomy-
dc.subject.keywordPlusextrahepatic bile duct obstruction-
dc.subject.keywordPlusfemale-
dc.subject.keywordPlushuman-
dc.subject.keywordPlusliver stiffness-
dc.subject.keywordPlusmale-
dc.subject.keywordAuthorExtrahepatic cholestasis-
dc.subject.keywordAuthorLiver stiffness-
dc.subject.keywordAuthorTransient elastography-
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Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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