Increased liver stiffness in extrahepatic cholestasis caused by choledocholithiasis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Trifan A. | - |
dc.contributor.author | Sfarti C. | - |
dc.contributor.author | Cojocariu C. | - |
dc.contributor.author | Dimache M. | - |
dc.contributor.author | Cretu M. | - |
dc.contributor.author | Hutanasu C. | - |
dc.contributor.author | Stanciu C. | - |
dc.contributor.author | Seo Y.S. | - |
dc.date.available | 2020-11-10T12:48:05Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1735-143X | - |
dc.identifier.issn | 1735-3408 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/31000 | - |
dc.description.abstract | Background: Extrahepatic cholestasis that is caused by benign and malignant diseases has been reported to increase liver stifness (LS), as measured by transient elastogra-phy (TE).Objectives: The aim of this study was to evaluate LS in patients with extrahepatic cholestasis due to choledocholithiasis before and after endoscopic sphincterotomy and stone removal.Patients and Methods: LS was measured by TE (Fibroscan) in patients with extrahepatic cholestasis that was caused by choledocholithiasis before and 1 month after endoscopic sphincterotomy and successful stone removal.Results: We studied 12 patients (7 females, 5 males), aged 36 to 76 years (mean age 57.1 ± 11.6 years), with extrahepatic cholestasis that was caused by choledocholithiasis. LS was increased in all patients (range: 6.2-18.4 kPa; mean: 8.9 ± 3.5 kPa) before endoscopic therapy. Successful biliary drainage was efected by sphincterotomy and stone removal in all patients, which led to a signifcant decline in LS to 3.9-8.1 kPa (Mean: 5.6 ± 1.2 kPa; p < 0.001) within a mean observation time of 29 days. The decrease in LS values correlated signifcantly with a decline in serum total bilirubin levels (r = 0.691; p < 0.0001).Conclusions: Extrahepatic cholestasis due to choledocholithiasis increases LS and should be excluded before assesing liver fbrosis by transient elastography © 2011, BRCGL, Published by Kowsar M.P.Co All right reserved. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Kowsar | - |
dc.title | Increased liver stiffness in extrahepatic cholestasis caused by choledocholithiasis | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.scopusid | 2-s2.0-79957647892 | - |
dc.identifier.bibliographicCitation | Hepatitis Monthly, v.11, no.5, pp 372 - 375 | - |
dc.citation.title | Hepatitis Monthly | - |
dc.citation.volume | 11 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 372 | - |
dc.citation.endPage | 375 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | bilirubin | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | aged | - |
dc.subject.keywordPlus | article | - |
dc.subject.keywordPlus | biliary tract drainage | - |
dc.subject.keywordPlus | biliary tract surgery | - |
dc.subject.keywordPlus | bilirubin blood level | - |
dc.subject.keywordPlus | clinical article | - |
dc.subject.keywordPlus | common bile duct stone | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | digestive tract parameters | - |
dc.subject.keywordPlus | elastography | - |
dc.subject.keywordPlus | endoscopic sphincterotomy | - |
dc.subject.keywordPlus | extrahepatic bile duct obstruction | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | liver stiffness | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordAuthor | Extrahepatic cholestasis | - |
dc.subject.keywordAuthor | Liver stiffness | - |
dc.subject.keywordAuthor | Transient elastography | - |
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