Clinical Characteristics and Prevalence of Comorbidities according to Metformin Use in Korean Patients with Type 2 Diabetes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chin, Sang Ouk | - |
dc.contributor.author | Ha, In Gyoon | - |
dc.contributor.author | Rhee, Sang Youl | - |
dc.contributor.author | Jeong, Su Jin | - |
dc.contributor.author | Chon, Suk | - |
dc.contributor.author | Kim, Sung Hoon | - |
dc.contributor.author | Ahn, Kyu Jeung | - |
dc.contributor.author | Baik, Sei Hyun | - |
dc.contributor.author | Park, Yongsoo | - |
dc.contributor.author | Nam, Moon Suk | - |
dc.contributor.author | Lee, Kwan Woo | - |
dc.contributor.author | Woo, Jeong Taek | - |
dc.date.available | 2020-12-09T08:46:29Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1687-8337 | - |
dc.identifier.issn | 1687-8345 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/33674 | - |
dc.description.abstract | Background/Aims This study was designed to identify the clinical characteristics of Korean patients with type 2 diabetes according to metformin use. Methods This cross-sectional study based on the Korean National Diabetes Program 2 registry used its baseline clinical data collected from seven participating university hospitals in Korea. Patients with no significant changes in their oral hypoglycemic agents and no diabetes-related complications within the year prior to participation were enrolled. Patients' clinical characteristics according to metformin use were analyzed. Results Among 858 subjects included in the analyses, 706 were metformin users and 152 were nonmetformin users. Metformin users were significantly younger and had higher and glycated hemoglobin with significantly lower rates of accompanying microvascular complications such as retinopathy, cataracts, overt proteinuria, renal insufficiency, and peripheral neuropathy than nonusers. Meanwhile, there was a significantly lower prevalence of malignancy and depression among metformin users. These associations remained significant in multivariate analyses. The prevalence rate of macrovascular complications was not significantly different between the two groups. Conclusions There were significant differences with respect to clinical characteristics and comorbidity prevalence according to metformin use among Korean type 2 diabetes patients. Long-term follow-up of these patients is necessary to observe how this difference will affect clinical outcomes for these patients. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Hindawi Publishing Corporation | - |
dc.title | Clinical Characteristics and Prevalence of Comorbidities according to Metformin Use in Korean Patients with Type 2 Diabetes | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1155/2020/9879517 | - |
dc.identifier.scopusid | 2-s2.0-85089302899 | - |
dc.identifier.wosid | 000558568000001 | - |
dc.identifier.bibliographicCitation | International Journal of Endocrinology, v.2020 | - |
dc.citation.title | International Journal of Endocrinology | - |
dc.citation.volume | 2020 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | CARDIOVASCULAR OUTCOMES | - |
dc.subject.keywordPlus | PRACTICE GUIDELINES | - |
dc.subject.keywordPlus | POSITION STATEMENT | - |
dc.subject.keywordPlus | CELL-PROLIFERATION | - |
dc.subject.keywordPlus | PANCREATIC-CANCER | - |
dc.subject.keywordPlus | SIGNALING PATHWAY | - |
dc.subject.keywordPlus | KIDNEY-DISEASE | - |
dc.subject.keywordPlus | MELLITUS | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | METAANALYSIS | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.