Lack of association between serotonin transporter promoter gene polymorphism and citalopram response in major depressive disorder
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Rhee-Hun | - |
dc.contributor.author | Choi, Myoung-Jin | - |
dc.contributor.author | Chang, Hun Soo | - |
dc.contributor.author | Hahn, Sang-Woo | - |
dc.contributor.author | Lee, Hwa-Young | - |
dc.contributor.author | Paik, Jong-Woo | - |
dc.contributor.author | Lim, Se-Won | - |
dc.contributor.author | Oh, Kang-Seob | - |
dc.contributor.author | Jung, Han-Yong | - |
dc.contributor.author | Lee, Min-Soo | - |
dc.date.available | 2020-12-09T10:21:11Z | - |
dc.date.issued | 2008-03-31 | - |
dc.identifier.issn | 1738-642X | - |
dc.identifier.issn | 2092-8467 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/35739 | - |
dc.description.abstract | The 5-HTT gene is a candidate gene for influencing the clinical response to antidepressant treatment. The purpose of this gene study was to determine the relationship between serotonin transporter gene polymorphism at the SLC6A4 and the response to citalopram in a Korean population with major depressive disorder (MDD). Citalopram was administered for 8 weeks to the 80 patients who completed this study. The severity of depression was assessed with the 21-item Hamilton Depression Rating scale, and the 5-HTTLPR genotypes in the patients were determined using the polymerase chain reaction. Our result did not showed significant differences in, allele, and carrier distribution between the normal group and MDD patients. This study suggest that polymorphism of the 5HTT gene was not associated with citalopram response to MDD in the Korean population. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC TOXICOGENOMICS & TOXICOPROTEOMICS | - |
dc.title | Lack of association between serotonin transporter promoter gene polymorphism and citalopram response in major depressive disorder | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.wosid | 000254600500001 | - |
dc.identifier.bibliographicCitation | MOLECULAR & CELLULAR TOXICOLOGY, v.4, no.1, pp 1 - 4 | - |
dc.citation.title | MOLECULAR & CELLULAR TOXICOLOGY | - |
dc.citation.volume | 4 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 4 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | kciCandi | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.subject.keywordPlus | ANTIDEPRESSANT RESPONSE | - |
dc.subject.keywordPlus | REUPTAKE INHIBITORS | - |
dc.subject.keywordPlus | REGION | - |
dc.subject.keywordPlus | FLUVOXAMINE | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordAuthor | MDD | - |
dc.subject.keywordAuthor | 5-HTTLPR | - |
dc.subject.keywordAuthor | polymorphism | - |
dc.subject.keywordAuthor | citalopram | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.