Long-Term Clinical Comparison of Procedural End Points After Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation Elimination of Nonpulmonary Vein Triggers Versus Noninducibility
DC Field | Value | Language |
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dc.contributor.author | Lee, Kwang-No | - |
dc.contributor.author | Roh, Seung-Young | - |
dc.contributor.author | Baek, Yong-Soo | - |
dc.contributor.author | Park, Hee-Soon | - |
dc.contributor.author | Ahn, Jinhee | - |
dc.contributor.author | Kim, Dong-Hyeok | - |
dc.contributor.author | Lee, Dae In | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Choi, Jong-Il | - |
dc.contributor.author | Park, Sang-Weon | - |
dc.contributor.author | Kim, Young-Hoon | - |
dc.date.available | 2020-11-02T07:47:38Z | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 1941-3149 | - |
dc.identifier.issn | 1941-3084 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/3885 | - |
dc.description.abstract | BACKGROUND: Pulmonary vein isolation (PVI) is effective for maintenance of sinus rhythm in 50% to 75% of patients with paroxysmal atrial fibrillation, and it is not uncommon for patients to require additional ablation after PVI. We prospectively evaluated the relative effectiveness of 2 post-PVI ablation strategies in paroxysmal atrial fibrillation. METHODS AND RESULTS: A total of 500 patients (mean age, 55.7 +/- 11.0 years; 74.6% male) were randomly assigned to undergo ablation by 2 different strategies after PVI: (1) elimination of non-PV triggers (group A, n=250) or (2) stepwise substrate modification including complex fractionated atrial electrogram or linear ablation until noninducibility of atrial tachyarrhythmia was achieved (group B, n=250). During a median follow-up of 26.0 months, 75 (32.2%) patients experienced at least 1 episode of recurrent atrial tachyarrhythmia after the single procedure in group A compared with 105 (43.8%) patients in group B (P value in log-rank test of Kaplan-Meier analysis: 0.012). Competing risk analysis showed that the cumulative incidence of atrial tachycardia was significantly higher in group B compared with group A (P=0.007). With the exception of total ablation time, there were no significant differences in fluoroscopic time or procedure-related complications between the 2 groups. CONCLUSIONS: Elimination of triggers as an end point of ablation in patients with paroxysmal atrial fibrillation decreased long-term recurrence of atrial tachyarrhythmia compared with a noninducibility approach achieved by additional empirical ablation. The post-PVI trigger test is thus a better end point of ablation for paroxysmal atrial fibrillation. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.title | Long-Term Clinical Comparison of Procedural End Points After Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation Elimination of Nonpulmonary Vein Triggers Versus Noninducibility | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1161/CIRCEP.117.005019 | - |
dc.identifier.scopusid | 2-s2.0-85047140287 | - |
dc.identifier.wosid | 000425356600002 | - |
dc.identifier.bibliographicCitation | CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, v.11, no.2 | - |
dc.citation.title | CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY | - |
dc.citation.volume | 11 | - |
dc.citation.number | 2 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | CATHETER ABLATION | - |
dc.subject.keywordPlus | ELECTROPHYSIOLOGICAL CHARACTERISTICS | - |
dc.subject.keywordPlus | CIRCUMFERENTIAL ABLATION | - |
dc.subject.keywordPlus | RADIOFREQUENCY ABLATION | - |
dc.subject.keywordPlus | LINEAR ABLATION | - |
dc.subject.keywordPlus | INDUCIBILITY | - |
dc.subject.keywordPlus | INITIATION | - |
dc.subject.keywordPlus | SUBSTRATE | - |
dc.subject.keywordPlus | FLUTTER | - |
dc.subject.keywordPlus | CONSEQUENCES | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | catheter ablation | - |
dc.subject.keywordAuthor | incidence | - |
dc.subject.keywordAuthor | recurrence | - |
dc.subject.keywordAuthor | tachycardia | - |
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