Clinical implications of pathologic factors after thyroid lobectomy in patients with papillary thyroid carcinoma
DC Field | Value | Language |
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dc.contributor.author | Park, Young Min | - |
dc.contributor.author | Lee, Doh Young | - |
dc.contributor.author | Oh, Kyung Ho | - |
dc.contributor.author | Cho, Jae-Gu | - |
dc.contributor.author | Baek, Seung-Kuk | - |
dc.contributor.author | Kwon, Soon-Young | - |
dc.contributor.author | Jung, Kwang-Yoon | - |
dc.contributor.author | Woo, Jeong-Soo | - |
dc.date.available | 2020-11-02T08:02:25Z | - |
dc.date.issued | 2017-12 | - |
dc.identifier.issn | 1368-8375 | - |
dc.identifier.issn | 1879-0593 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/4367 | - |
dc.description.abstract | Objective: We evaluated the clinical and prognostic significance of pathologic factors by analyzing the treatment results of patients who underwent thyroid lobectomy. Materials and methods: We retrospectively analyzed data from 734 patients diagnosed with papillary thyroid cancer who underwent thyroid lobectomy at Korea University Hospital from January 2004 to December 2016. Results: A total of 734 patients were included in the study and their mean age was 44.5 years (range, 15-83). On univariate analysis, tumor size and recurrence-free survival were significantly related. The 10-year recurrence-free survival was 98.3% for tumors <= 1 cm, 77.8% for > 1 cm and <= 2 cm, and 66.7% for > 2 cm (p = 0.014). Recurrence-free survival was significantly different between patients with and without microscopic extrathyroidal extension (p = 0.002). The 10-year recurrence-free survival rate was 99.2% for patients without extrathyroidal extension and 92.2% for patients with microscopic extrathyroidal extension. Multivariate analysis showed only microscopic extrathyroidal extension was significantly correlated with recurrence-free survival (p = 0.029). Conclusion: In patients undergoing thyroid lobectomy for low-risk papillary thyroid cancer, microscopic extrathyroidal extension was an important prognostic factor associated with recurrence-free survival. However, in cases with microscopic extrathyroidal extension findings on postoperative pathologic examination, appropriate ultrasonographic follow-up of the contralateral thyroid lobe and cervical lymph node to facilitate early detection and prompt treatment of recurrence can control the disease without a deterioration of survival rate. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | Clinical implications of pathologic factors after thyroid lobectomy in patients with papillary thyroid carcinoma | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.oraloncology.2017.10.012 | - |
dc.identifier.scopusid | 2-s2.0-85031757344 | - |
dc.identifier.wosid | 000417555400001 | - |
dc.identifier.bibliographicCitation | ORAL ONCOLOGY, v.75, pp 1 - 5 | - |
dc.citation.title | ORAL ONCOLOGY | - |
dc.citation.volume | 75 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 5 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Dentistry, Oral Surgery & Medicine | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Dentistry, Oral Surgery & Medicine | - |
dc.subject.keywordPlus | MICROSCOPIC EXTRATHYROIDAL EXTENSION | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | MICROCARCINOMA | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordAuthor | Pathologic factor | - |
dc.subject.keywordAuthor | Recurrence | - |
dc.subject.keywordAuthor | Papillary thyroid carcinoma | - |
dc.subject.keywordAuthor | Thyroid lobectomy | - |
dc.subject.keywordAuthor | Microscopic extrathyroidal extension | - |
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