Clinical comparison between the presence and absence of protein plugs in pediatric choledochal cysts: experience in 390 patients over 30 years in a single center
DC Field | Value | Language |
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dc.contributor.author | Oh, Chaeyoun | - |
dc.contributor.author | Cheun, Jong-Ho | - |
dc.contributor.author | Kim, Hyun-Young | - |
dc.date.accessioned | 2021-11-29T08:40:09Z | - |
dc.date.available | 2021-11-29T08:40:09Z | - |
dc.date.issued | 2021-11 | - |
dc.identifier.issn | 2288-6575 | - |
dc.identifier.issn | 2288-6796 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/54782 | - |
dc.description.abstract | Purpose: The incidence of choledochal cyst (CC) with protein plugs is between 15.5%-40.4%. However, studies on CCs with protein plugs in children are limited. We aimed to analyze the clinical features, surgical findings, and complications of pediatric CCs with and without protein plugs. Methods: We retrospectively analyzed 390 patients who underwent surgery for CCs between January 1987 and September 2017. The patients were divided into 2 groups: groups A (CC with protein plugs) and B (CC without protein plugs). The presence of protein plugs was evaluated using preoperative images or identified during surgery. Results: One hundred forty-two (36.4%) patients had protein plugs in the pancreaticobiliary duct. The most common initial clinical presentation was abdominal pain, and its incidence was significantly higher in group A (66.2%) than in group B (54.8%) (P = 0.032). The incidence of accompanying pancreatitis was also significantly higher in group A (37.3% vs. 27.0%) (P = 0.040). Anomalous pancreaticobiliary ductal union (APBDU) was found in 261 patients (66.9%) and its incidence was significantly higher in group A (74.6% vs. 62.5%) (P = 0.014). Most protein plugs were found in the cyst (88.0%) and common channel (31.7%). The incidence of early complications was higher in group A; conversely, that of late complications did not differ. Conclusion: Approximately 36.4% of the pediatric CC patients were accompanied by protein plugs. Abdominal pain, pancreatitis, and APBDU were more commonly observed among those with protein plugs than among those without; long-term complications did not differ between them. [Ann Surg Treat Res 2021;101(5):306-313] | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한외과학회 | - |
dc.title | Clinical comparison between the presence and absence of protein plugs in pediatric choledochal cysts: experience in 390 patients over 30 years in a single center | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.4174/astr.2021.101.5.306 | - |
dc.identifier.wosid | 000717011400007 | - |
dc.identifier.bibliographicCitation | Annals of Surgical Treatment and Research, v.101, no.5, pp 306 - 313 | - |
dc.citation.title | Annals of Surgical Treatment and Research | - |
dc.citation.volume | 101 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 306 | - |
dc.citation.endPage | 313 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002770563 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY | - |
dc.subject.keywordPlus | PANCREATIC COMPLICATIONS | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | SAFETY | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | UNION | - |
dc.subject.keywordPlus | ERCP | - |
dc.subject.keywordAuthor | Child | - |
dc.subject.keywordAuthor | Choledochal cyst | - |
dc.subject.keywordAuthor | Pediatrics | - |
dc.subject.keywordAuthor | Protein plug | - |
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