Accuracy of human papillomavirus tests on self-collected urine versus clinician-collected samples for the detection of cervical precancer: a systematic review and meta-analysis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Hyun-Woong | - |
dc.contributor.author | Shim, Sung Ryul | - |
dc.contributor.author | Lee, Jae Kwan | - |
dc.contributor.author | Hong, Jin Hwa | - |
dc.date.accessioned | 2022-01-28T01:40:19Z | - |
dc.date.available | 2022-01-28T01:40:19Z | - |
dc.date.issued | 2022-01 | - |
dc.identifier.issn | 2005-0380 | - |
dc.identifier.issn | 2005-0399 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/55099 | - |
dc.description.abstract | Objective: The human papillomavirus (HPV) test is an effective screening tool to prevent cervical cancer. Urinary sampling for HPV detection improves the accessibility and participation of screening services and reduces the cost and burden on physicians. The clinical accuracy of urinary HPV test has yet to be determined via meta-analysis. This study assessed the clinical accuracy of these tests to detect cervical intraepithelial neoplasia (CIN) 2 or worse. Methods: Relevant studies were identified using the PubMed, Embase, and Cochrane databases. Research eligibility was based on the clinical accuracy of HPV test on clinician- collected samples as a comparator test, and urine as an index test. The reference standard was the presence of CIN2 or worse. The pooled absolute, relative sensitivity, and specificity of the urinary HPV test versus clinician-collected samples were assessed using a bivariate model. Results: The pooled sensitivity of urinary HPV test was significantly lower than thatof clinician-collected samples (ratio=0.84, 95% confidence interval [CI]=0.78–0.91). However, some polymerase chain reaction (PCR)-based HPV test such as GP5+/6+ (relative sensitivity=0.98, 95% CI=0.91–1.05), SPF10 (relative sensitivity=0.98, 85% CI=0.88–1.08) and non GP5+/6+ PCR (relative sensitivity=1.00, 95% CI=0.88–1.14) showed similar sensitivity in both the urine and clinician-collected samples. Conclusion: Our findings indicate that HPV test with some PCR-based assay on urine versus clinician-collected samples demonstrate similar clinical accuracy to detect CIN2 or worse. It suggests that urinary HPV test may present itself as a decent alternative screening tool for the detection of cervical pre-cancer. | - |
dc.format.extent | 16 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한부인종양학회 | - |
dc.title | Accuracy of human papillomavirus tests on self-collected urine versus clinician-collected samples for the detection of cervical precancer: a systematic review and meta-analysis | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3802/jgo.2022.33.e4 | - |
dc.identifier.scopusid | 2-s2.0-85121971305 | - |
dc.identifier.wosid | 000740725100009 | - |
dc.identifier.bibliographicCitation | Journal of Gynecologic Oncology, v.33, no.1, pp 1 - 16 | - |
dc.citation.title | Journal of Gynecologic Oncology | - |
dc.citation.volume | 33 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 16 | - |
dc.identifier.kciid | ART002799171 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.subject.keywordPlus | RISK HUMAN-PAPILLOMAVIRUS | - |
dc.subject.keywordPlus | HPV DETECTION | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | PERFORMANCE | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordPlus | VULVAR | - |
dc.subject.keywordPlus | ASSAY | - |
dc.subject.keywordAuthor | Cervical Intraepithelial Neoplasia | - |
dc.subject.keywordAuthor | Human Papillomavirus DNA Test | - |
dc.subject.keywordAuthor | Urine | - |
dc.subject.keywordAuthor | Uterine Cervical Neoplasms | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.