Intra-abdominal hypertension does not predict renal recovery or in-hospital mortality in critically ill patients with acute kidney injury
DC Field | Value | Language |
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dc.contributor.author | Chang H.J. | - |
dc.contributor.author | Yang J. | - |
dc.contributor.author | Kim S.C. | - |
dc.contributor.author | Kim M.-G. | - |
dc.contributor.author | Jo S.-K. | - |
dc.contributor.author | Cho W.-Y. | - |
dc.contributor.author | Kim H.-K. | - |
dc.date.available | 2020-11-02T16:43:02Z | - |
dc.date.issued | 2015-06-01 | - |
dc.identifier.issn | 2211-9132 | - |
dc.identifier.issn | 2211-9140 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/8422 | - |
dc.description.abstract | Background Although emerging evidence suggests that intra-abdominal hypertension (IAH) is a predictor of the development of acute kidney injury (AKI), it remains unclear whether the presence of IAH is a predictor of prognosis in patients with AKI. The purpose of this study was to assess whether the presence of IAH could predict prognosis in critically ill patients with AKI. The prognostic value of urinary biomarkers was also determined. Methods In this prospective observational study, we enrolled 57 patients with established AKI, who were admitted to the intensive care unit between February 2012 and June 2014. IAH was defined as a sustained elevation in intra-abdominal pressure of ≥12 mmHg, in three consecutive measurements performed daily on the first 3 days. Urinary neutrophil gelatinase-associated lipocalin (NGAL), liver-type fatty acid-binding protein, and simplified acute physiology score II score at the time of admission were also examined. Results IAH was observed in 78.9% of patients. The in-hospital mortality was 21.1%, and renal recovery during hospitalization was achieved in 40.4% of patients. Although high urinary NGAL [odds ratio (OR), 1.015] and liver-type fatty acid-binding protein (OR, 1.003) were found to be independent predictors of renal recovery, IAH was not. High urinary NGAL (OR, 1.003) and a high simplified acute physiology score II score (OR, 1.102) were independent predictors of in-hospital mortality, while IAH or urinary liver-type fatty acid-binding protein was not. Conclusion Although IAH is prevalent in critically ill patients with AKI, it did not predict AKI prognosis. However, urinary NGAL was found to be a useful predictor of both renal recovery and in-hospital mortality. © 2015. The Korean Society of Nephrology. Published by Elsevier. All rights reserved. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier | - |
dc.title | Intra-abdominal hypertension does not predict renal recovery or in-hospital mortality in critically ill patients with acute kidney injury | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.1016/j.krcp.2015.03.004 | - |
dc.identifier.scopusid | 2-s2.0-84937525813 | - |
dc.identifier.bibliographicCitation | Kidney Research and Clinical Practice, v.34, no.2, pp 103 - 108 | - |
dc.citation.title | Kidney Research and Clinical Practice | - |
dc.citation.volume | 34 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 103 | - |
dc.citation.endPage | 108 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002003862 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | biological marker | - |
dc.subject.keywordPlus | fatty acid binding protein | - |
dc.subject.keywordPlus | neutrophil gelatinase associated lipocalin | - |
dc.subject.keywordPlus | abdominal pressure | - |
dc.subject.keywordPlus | acute kidney failure | - |
dc.subject.keywordPlus | aged | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | convalescence | - |
dc.subject.keywordPlus | critically ill patient | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | hospitalization | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | intraabdominal hypertension | - |
dc.subject.keywordPlus | major clinical study | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | mortality | - |
dc.subject.keywordPlus | observational study | - |
dc.subject.keywordPlus | prediction | - |
dc.subject.keywordPlus | priority journal | - |
dc.subject.keywordPlus | prognosis | - |
dc.subject.keywordPlus | prospective study | - |
dc.subject.keywordAuthor | Acute kidney injury | - |
dc.subject.keywordAuthor | Intra-abdominal hypertension | - |
dc.subject.keywordAuthor | Prognosis | - |
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