The prevalence rate of tuberculin skin test positive by contacts group to predict the development of active tuberculosis after school outbreaks
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim H.J. | - |
dc.contributor.author | Chun B.C. | - |
dc.contributor.author | Kwon A.M. | - |
dc.contributor.author | Lee G.-H. | - |
dc.contributor.author | Ryu S. | - |
dc.contributor.author | Oh S.Y. | - |
dc.contributor.author | Lee J.B. | - |
dc.contributor.author | Yoo S.H. | - |
dc.contributor.author | Kim E.S. | - |
dc.contributor.author | Kim J.H. | - |
dc.contributor.author | Shin C. | - |
dc.contributor.author | Lee S.H. | - |
dc.date.available | 2020-11-02T16:43:03Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1738-3536 | - |
dc.identifier.issn | 2005-6184 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/8424 | - |
dc.description.abstract | Background: The tuberculin skin test (TST) is the standard tool to diagnose latent tuberculosis infection (LTBI) in mass screening. The aim of this study is to find an optimal cut-off point of the TST+ rate within tuberculosis (TB) contacts to predict the active TB development among adolescents in school TB outbreaks. Methods: The Korean National Health Insurance Review and Assessment database was used to identify active TB development in relation to the initial TST (cut-off, 10 mm). The 7,475 contacts in 89 schools were divided into two groups: Incident TB group (43 schools) and no incident TB group (46 schools). LTBI treatment was initiated in 607 of the 1,761 TST+ contacts. The association with active TB progression was examined at different cut-off points of the TST+ rate. Results: The mean duration of follow-up was 3.9±0.9 years. Thirty-three contacts developed active TB during the 4,504 person-years among the TST+ contacts without LTBI treatment (n=1,154). The average TST+ rate for the incident TB group (n=43) and no incident TB group (n=46) were 31.0% and 15.5%, respectively. The TST+ rate per group was related with TB progression (odds ratio [OR], 1.025; 95% confidence interval [CI], 1.001-1.050; p=0.037). Based on the TST+ rate per group, active TB was best predicted at TST+ ≥ 16% (OR, 3.11; 95% CI, 1.29-7.51; area under curve, 0.64). Conclusion: Sixteen percent of the TST+ rate per group within the same grade students can be suggested as an optimal cut-off to predict active TB development in middle and high schools TB outbreaks. Copyright © 2015 The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Korean National Tuberculosis Association | - |
dc.title | The prevalence rate of tuberculin skin test positive by contacts group to predict the development of active tuberculosis after school outbreaks | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.4046/trd.2015.78.4.349 | - |
dc.identifier.scopusid | 2-s2.0-84953750892 | - |
dc.identifier.bibliographicCitation | Tuberculosis and Respiratory Diseases, v.78, no.4, pp 349 - 355 | - |
dc.citation.title | Tuberculosis and Respiratory Diseases | - |
dc.citation.volume | 78 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 349 | - |
dc.citation.endPage | 355 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002035682 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | adolescent | - |
dc.subject.keywordPlus | adolescent disease | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | area under the curve | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | bibliographic database | - |
dc.subject.keywordPlus | disease association | - |
dc.subject.keywordPlus | disease course | - |
dc.subject.keywordPlus | epidemic | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | follow up | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | major clinical study | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | national health insurance | - |
dc.subject.keywordPlus | school | - |
dc.subject.keywordPlus | tuberculin test | - |
dc.subject.keywordPlus | tuberculosis | - |
dc.subject.keywordPlus | child | - |
dc.subject.keywordPlus | comparative study | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | epidemic | - |
dc.subject.keywordPlus | incidence | - |
dc.subject.keywordPlus | latent tuberculosis | - |
dc.subject.keywordPlus | mass screening | - |
dc.subject.keywordPlus | medical history | - |
dc.subject.keywordPlus | prediction | - |
dc.subject.keywordPlus | prevalence | - |
dc.subject.keywordPlus | Review | - |
dc.subject.keywordPlus | thorax radiography | - |
dc.subject.keywordAuthor | Adolescent | - |
dc.subject.keywordAuthor | Disease outbreaks | - |
dc.subject.keywordAuthor | Latent tuberculosis | - |
dc.subject.keywordAuthor | Tuberculin test | - |
dc.subject.keywordAuthor | Tuberculosis | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.