초기 절제술 16년 후 다발성 원격 전이된 악성 부신경절종 1예

Abstract

Paragangliomas are rare tumors that arise from the extra-adrenal chromaffin cells, and malignancy is defined by the presence ofmetastases to sites that normally lack chromaffin tissue. The main therapeutic targets are tumor reduction and control of excessivecatecholamine secretion. Currently, the adjuvant therapy to surgery is radiotherapy treatment using high-dose MIBG; chemotherapyis currently evolving. We report herein a case of malignant paraganglioma with lung and spine metastasis that occurred 16 years afterprimary tumor excision and was treated with high dose MIBG radiotherapy and chemotherapy.