Sex-Related Differences in Left Atrial Low-Voltage Areas According to CHA(2)DS(2)-VA Scores among Patients with Atrial Fibrillation
DC Field | Value | Language |
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dc.contributor.author | Kim, Do Young | - |
dc.contributor.author | Kim, Yun Gi | - |
dc.contributor.author | Choi, Ha Young | - |
dc.contributor.author | Choi, Yun Young | - |
dc.contributor.author | Boo, Ki Yung | - |
dc.contributor.author | Lee, Kwang-No | - |
dc.contributor.author | Roh, Seung-Young | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Choi, Jong-Il | - |
dc.contributor.author | Kim, Young-Hoon | - |
dc.date.accessioned | 2022-06-21T00:40:16Z | - |
dc.date.available | 2022-06-21T00:40:16Z | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61065 | - |
dc.description.abstract | (1) Background: We hypothesized that female sex would have a differential impact on left atrial (LA) low-voltage areas (LVAs) according to CHA(2)DS(2)-VA scores. (2) Methods: This study included 553 patients who underwent radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). LVAs were defined as regions with bipolar peak-to-peak voltages of <0.5 mV. The proportion of LVAs was calculated by dividing the total LVA by the LA surface area. (3) Results: There was no sex-related difference in LA LVAs among patients with a CHA(2)DS(2)-VA scores <= 2. The proportion of LVAs was significantly higher in females among patients with CHA(2)DS(2)-VA scores of 3 or 4 (10.1 (4.7-15.1)% vs. 15.8 (9.2-32.1)%; p = 0.027). Female sex was significantly associated with extensive LVAs (LVA proportion >= 30%). Females had odd ratios of 27.82 (95% confidence interval (CI) 3.33-756.8, p = 0.01), and 1.53 (95% CI 0.81-2.83, p = 0.184) for extensive LAVs in patients with CHA(2)DS(2)-VA scores >= 3 and CHA(2)DS(2)-VA scores < 3, respectively. In the multiple regression model, female patients with a CHA(2)DS(2)-VA >= 3 were significantly associated with a higher proportion of LVAs (beta = 8.52, p = 0.039). (4) Conclusions: Female sex was significantly associated with extensive LVAs, particularly when their CHA(2)DS(2)-VA scores were >= 3. This result suggests that female sex has a differential effect on the extent of LVAs based on the presence of additional risk factors. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI AG | - |
dc.title | Sex-Related Differences in Left Atrial Low-Voltage Areas According to CHA(2)DS(2)-VA Scores among Patients with Atrial Fibrillation | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/jcm11113111 | - |
dc.identifier.scopusid | 2-s2.0-85131160336 | - |
dc.identifier.wosid | 000808686200001 | - |
dc.identifier.bibliographicCitation | Journal of Clinical Medicine, v.11, no.11 | - |
dc.citation.title | Journal of Clinical Medicine | - |
dc.citation.volume | 11 | - |
dc.citation.number | 11 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | EXTRACELLULAR-MATRIX | - |
dc.subject.keywordPlus | FEMALE SEX | - |
dc.subject.keywordPlus | STROKE | - |
dc.subject.keywordPlus | FIBROSIS | - |
dc.subject.keywordPlus | GENDER | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordPlus | DEATH | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordPlus | AGE | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | catheter ablation | - |
dc.subject.keywordAuthor | female | - |
dc.subject.keywordAuthor | sex | - |
dc.subject.keywordAuthor | electro-anatomical remodeling | - |
dc.subject.keywordAuthor | low voltage area | - |
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