Pretransplant and Posttransplant Alcohol Consumption and Outcomes in Kidney Transplantation: A Prospective Multicenter Cohort Study
DC Field | Value | Language |
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dc.contributor.author | Jung, Hee-Yeon | - |
dc.contributor.author | Jeon, Yena | - |
dc.contributor.author | Huh, Kyu Ha | - |
dc.contributor.author | Park, Jae Berm | - |
dc.contributor.author | Kim, Myung-Gyu | - |
dc.contributor.author | Lee, Sik | - |
dc.contributor.author | Han, Seungyeup | - |
dc.contributor.author | Ro, Han | - |
dc.contributor.author | Yang, Jaeseok | - |
dc.contributor.author | Ahn, Curie | - |
dc.contributor.author | Cho, Jang-Hee | - |
dc.contributor.author | Park, Sun-Hee | - |
dc.contributor.author | Kim, Yong-Lim | - |
dc.contributor.author | Kim, Chan-Duck | - |
dc.date.accessioned | 2022-07-27T00:40:30Z | - |
dc.date.available | 2022-07-27T00:40:30Z | - |
dc.date.issued | 2022-05 | - |
dc.identifier.issn | 0934-0874 | - |
dc.identifier.issn | 1432-2277 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61226 | - |
dc.description.abstract | The impact of pretransplant and posttransplant alcohol consumption on outcomes in kidney transplant recipients (KTRs) is uncertain. Self-reported alcohol consumption was obtained at the time of transplant and 2 years after transplant in a prospective cohort study. Among 907 KTRs, 368 (40.6%) were drinkers at the time of transplant. Compared to non-drinkers, alcohol consumption did not affect the risk of death-censored graft failure (DCGF), biopsy-proven acute rejection (BPAR), cardiovascular events, or all-cause mortality. Compared to persistent non-drinkers, the development of DCGF, BPAR, cardiovascular events, all-cause mortality, or posttransplant diabetes mellitus was not affected by the alcohol consumption pattern (persistent, de novo, or stopped drinking) over time. However, de novo drinkers had a significantly higher total cholesterol (p < 0.001) and low-density lipoprotein cholesterol levels (p = 0.005) compared to persistent non-drinkers 5 years after transplant, and had significantly higher total cholesterol levels (p = 0.002) compared to the stopped drinking group 7 years after transplant, even after adjusting for the use of lipid-lowering agents, age, sex, and body mass index. Although pretransplant and posttransplant alcohol consumption were not associated with major outcomes in KTRs during the median follow-up of 6.0 years, a new start of alcohol use after KT results in a relatively poor lipid profile. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | Pretransplant and Posttransplant Alcohol Consumption and Outcomes in Kidney Transplantation: A Prospective Multicenter Cohort Study | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.3389/ti.2022.10243 | - |
dc.identifier.scopusid | 2-s2.0-85132082150 | - |
dc.identifier.wosid | 000822717200001 | - |
dc.identifier.bibliographicCitation | Transplant International, v.35 | - |
dc.citation.title | Transplant International | - |
dc.citation.volume | 35 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.subject.keywordPlus | INSULIN SENSITIVITY | - |
dc.subject.keywordPlus | CHOLESTEROL LEVELS | - |
dc.subject.keywordPlus | FUNCTION DECLINE | - |
dc.subject.keywordPlus | ALL-CAUSE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | METABOLISM | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | DRINKERS | - |
dc.subject.keywordAuthor | kidney transplantation | - |
dc.subject.keywordAuthor | alcohol | - |
dc.subject.keywordAuthor | all-cause mortality | - |
dc.subject.keywordAuthor | biopsy-proven acute rejection | - |
dc.subject.keywordAuthor | cardiovascular events | - |
dc.subject.keywordAuthor | death-censored graft failure | - |
dc.subject.keywordAuthor | low-density lipoprotein cholesterol | - |
dc.subject.keywordAuthor | total cholesterol | - |
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