Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Non-Renal Risk Factors for Chronic Kidney Disease in Liver Recipients with Functionally Intact Kidneys at 1 Month

Full metadata record
DC FieldValueLanguage
dc.contributor.authorKim, Deok-Gie-
dc.contributor.authorHwang, Shin-
dc.contributor.authorKim, Jong Man-
dc.contributor.authorRyu, Je Ho-
dc.contributor.authorYou, Young Kyoung-
dc.contributor.authorChoi, Donglak-
dc.contributor.authorKim, Bong-Wan-
dc.contributor.authorKim, Dong-Sik-
dc.contributor.authorNah, Yang Won-
dc.contributor.authorKim, Tae-Seok-
dc.contributor.authorCho, Jai Young-
dc.contributor.authorHong, Geun-
dc.contributor.authorYang, Jae Do-
dc.contributor.authorHan, Jaryung-
dc.contributor.authorSuh, Suk-Won-
dc.contributor.authorKim, Kwan Woo-
dc.contributor.authorJung, Yun Kyung-
dc.contributor.authorMoon, Ju Ik-
dc.contributor.authorLee, Jun Young-
dc.contributor.authorKim, Sung Hwa-
dc.contributor.authorLee, Jae Geun-
dc.contributor.authorKim, Myoung Soo-
dc.contributor.authorLee, Kwang-Woong-
dc.contributor.authorJoo, Dong Jin-
dc.contributor.authorKorean Organ Transplantation Registry Study Group-
dc.contributor.authorYu, Young Dong(KOTRY Study Group)-
dc.contributor.authorJo, Hye-Sung(KOTRY Study Group)-
dc.contributor.authorPark, PyoungJae(KOTRY Study Group)-
dc.contributor.authorKim, Wan-Joon(KOTRY Study Group)-
dc.date.accessioned2022-08-17T23:40:08Z-
dc.date.available2022-08-17T23:40:08Z-
dc.date.created2022-08-16-
dc.date.issued2022-07-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61339-
dc.description.abstractChronic kidney disease (CKD) is a critical complication of liver transplants, of which non-renal risk factors are not fully understood yet. This study aimed to reveal pre- and post-transplant risk factors for CKD (<60 mL/min/1.73 m(2)), examining liver recipients with functionally intact kidneys one month after grafting using nationwide cohort data. Baseline risk factors were analyzed with multivariable Cox regression analyses and post-transplant risk factors were investigated with the time-dependent Cox model and matched analyses of time-conditional propensity scores. Of the 2274 recipients with a one-month eGFR >= 60 mL/min/1.73 m(2), 494 (22.3%) developed CKD during a mean follow-up of 36.6 +/- 14.4 months. Age, female sex, lower body mass index, pre-transplant diabetes mellitus, and lower performance status emerged as baseline risk factors for CKD. Time-dependent Cox analyses revealed that recurrent hepatocellular carcinoma (HR = 1.93, 95% CI 1.06-3.53) and infection (HR = 1.44, 95% CI 1.12-1.60) were significant post-transplant risk factors for CKD. Patients who experienced one of those factors showed a significantly higher risk of subsequent CKD compared with the matched controls who lacked these features (p = 0.013 for recurrent hepatocellular carcinoma, and p = 0.003 for infection, respectively). This study clarifies pre- and post-transplant non-renal risk factors, which lead to renal impairment after LT independently from patients' renal functional reserve.-
dc.language영어-
dc.language.isoen-
dc.publisherMDPI AG-
dc.titleNon-Renal Risk Factors for Chronic Kidney Disease in Liver Recipients with Functionally Intact Kidneys at 1 Month-
dc.typeArticle-
dc.contributor.affiliatedAuthorKim, Dong-Sik-
dc.contributor.affiliatedAuthorYu, Young Dong(KOTRY Study Group)-
dc.contributor.affiliatedAuthorJo, Hye-Sung(KOTRY Study Group)-
dc.contributor.affiliatedAuthorPark, PyoungJae(KOTRY Study Group)-
dc.contributor.affiliatedAuthorKim, Wan-Joon(KOTRY Study Group)-
dc.identifier.doi10.3390/jcm11144203-
dc.identifier.scopusid2-s2.0-85137276329-
dc.identifier.wosid000833725600001-
dc.identifier.bibliographicCitationJournal of Clinical Medicine, v.11, no.14-
dc.relation.isPartOfJournal of Clinical Medicine-
dc.citation.titleJournal of Clinical Medicine-
dc.citation.volume11-
dc.citation.number14-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaGeneral & Internal Medicine-
dc.relation.journalWebOfScienceCategoryMedicine, General & Internal-
dc.subject.keywordPlusHEPATOCELLULAR-CARCINOMA-
dc.subject.keywordPlusRENAL-DISEASE-
dc.subject.keywordPlusTRANSPLANTATION-
dc.subject.keywordPlusTACROLIMUS-
dc.subject.keywordPlusEVEROLIMUS-
dc.subject.keywordPlusMORTALITY-
dc.subject.keywordPlusEFFICACY-
dc.subject.keywordPlusOUTCOMES-
dc.subject.keywordPlusIMPACT-
dc.subject.keywordPlusSAFETY-
dc.subject.keywordAuthorliver transplantation-
dc.subject.keywordAuthorchronic kidney disease-
dc.subject.keywordAuthorrenal dysfunction-
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Transplantation and Vascular Surgery > 1. Journal Articles
2. Clinical Science > Department of Hepato-Biliary-Pancreatic Surgery > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Kim, Wan Joon photo

Kim, Wan Joon
Guro Hospital (Department of Hepato-Biliary-Pancreatic Surgery, Guro Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE