Utricular dysfunction in patients with orthostatic hypotension
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jae-Gyum | - |
dc.contributor.author | Lee, Jeong-Heon | - |
dc.contributor.author | Lee, Sun-Uk | - |
dc.contributor.author | Choi, Jeong-Yoon | - |
dc.contributor.author | Kim, Byung-Jo | - |
dc.contributor.author | Kim, Ji-Soo | - |
dc.date.accessioned | 2022-09-26T02:40:17Z | - |
dc.date.available | 2022-09-26T02:40:17Z | - |
dc.date.issued | 2022-12 | - |
dc.identifier.issn | 0959-9851 | - |
dc.identifier.issn | 1619-1560 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61508 | - |
dc.description.abstract | Purpose To delineate the association between otolithic dysfunction and orthostatic hypotension (OH). Methods We retrospectively reviewed the medical records of 382 patients who presented with orthostatic dizziness at a tertiary dizziness center between July 2017 and December 2021. Patients were included for analyses when they had completed ocular (oVEMP) and/or cervical vestibular-evoked myogenic potentials (cVEMP), and head-up tilt table test with a Finometer (n = 155). We compared the results between the patients with OH (n = 38) and those with NOI (normal head-up tilt table test despite orthostatic intolerance, n = 117). Results Thirty-eight patients with OH were further categorized as either classic (n = 30), delayed (n = 7), or initial (n = 1) types. Multivariable logistic regression showed that OH was associated with high baseline systolic BP (p = 0.046), presence of heart failure (p = 0.016), and unilateral oVEMP abnormalities (p = 0.016). n1 latency of oVEMP were negatively correlated with the maximal changes of systolic blood pressure (BP) in 15 s (ΔSBP15s, p = 0.013), 3 min (ΔSBP3min, p = 0.005) and 10 min (ΔSBP10min, p = 0.002). In contrast, the n1-p1 amplitude was positively correlated with ΔSBP15s (p = 0.029). Meanwhile, p13 latency of cVEMP was negatively correlated with ΔSBP10min (p = 0.018). Conclusions Our study provides evidence of utricular dysfunction related to OH. | - |
dc.format.extent | 14 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Dr. Dietrich Steinkopff Verlag | - |
dc.title | Utricular dysfunction in patients with orthostatic hypotension | - |
dc.type | Article | - |
dc.publisher.location | 독일 | - |
dc.identifier.doi | 10.1007/s10286-022-00890-1 | - |
dc.identifier.scopusid | 2-s2.0-85137593602 | - |
dc.identifier.wosid | 000852264600001 | - |
dc.identifier.bibliographicCitation | Clinical Autonomic Research, v.32, no.6, pp 431 - 444 | - |
dc.citation.title | Clinical Autonomic Research | - |
dc.citation.volume | 32 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 431 | - |
dc.citation.endPage | 444 | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | EVOKED MYOGENIC POTENTIALS | - |
dc.subject.keywordPlus | SYMPATHETIC-NERVE ACTIVITY | - |
dc.subject.keywordPlus | FREQUENCY PHYSIOLOGICAL ACTIVATION | - |
dc.subject.keywordPlus | BLOOD-PRESSURE | - |
dc.subject.keywordPlus | VESTIBULAR STIMULATION | - |
dc.subject.keywordPlus | NUCLEUS NEURONS | - |
dc.subject.keywordPlus | CARDIAC-OUTPUT | - |
dc.subject.keywordPlus | CONSCIOUS CATS | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordPlus | RESPONSES | - |
dc.subject.keywordAuthor | Orthostatic hypotension | - |
dc.subject.keywordAuthor | Autonomic nervous system | - |
dc.subject.keywordAuthor | Otolith | - |
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