Identifying fragile calcifications of the aortic valve in transcatheter aortic valve replacement: iodine concentration of aortic valvular calcification by spectral CT
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Soojung | - |
dc.contributor.author | Cho, Yongwon | - |
dc.contributor.author | Oh, Yu-Whan | - |
dc.contributor.author | Ko, Minseok | - |
dc.contributor.author | Lim, Do-Sun | - |
dc.contributor.author | Yu, Cheol Woong | - |
dc.contributor.author | Park, Seong-Mi | - |
dc.contributor.author | Kim, Mi-Na | - |
dc.contributor.author | Hwang, Sung Ho | - |
dc.date.accessioned | 2022-10-05T00:40:16Z | - |
dc.date.available | 2022-10-05T00:40:16Z | - |
dc.date.issued | 2023-03 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.issn | 1432-1084 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61532 | - |
dc.description.abstract | Objective To demonstrate the relationship between spectral computed tomography (CT) measured iodine concentration and strength of aortic valvular calcification (AVC) in patients with aortic valve stenosis (AVS). Methods A retrospective study was performed on patients who underwent transcatheter aortic valve replacement (TAVR) for symptomatic AVS and underwent both pre and postprocedural electrocardiogram gated CT scans using a spectral CT system. Preprocedural CT was used to evaluate the volume and iodine concentration (IC) in the AVC. Postprocedural CT data were used to calculate the volume reduction percentage (VRP) of AVC. Multiple linear regression analysis was used to identify the independent variables related to the VRP in AVCs. Results A total of 94 AVCs were selected from 22 patients. The mean volume and IC of the AVCs before TAVR were 0.37 mL ± 0.15 mL and 7 mg/mL ± 10.5 mg/mL, respectively. After TAVR, a median VRP of all 94 AVCs was 18.5%. Multiple linear regression analysis showed that the IC was independently associated with the VRP (coefficient = 1.64, p < 0.001). When an optimal IC cutoff point was set at 4 mg/mL in the assessment of a fragile AVC which showed the VRP was > 18.5%, the sensitivity was 63%; specificity, 91%; positive predictive value, 88%; and negative predictive value, 71%. Conclusions When using spectral CT to prepare the TAVR, measuring the IC of the AVC may be useful to assess the probability of AVC deformity after TAVR. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Identifying fragile calcifications of the aortic valve in transcatheter aortic valve replacement: iodine concentration of aortic valvular calcification by spectral CT | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1007/s00330-022-09133-3 | - |
dc.identifier.scopusid | 2-s2.0-85138147087 | - |
dc.identifier.wosid | 000854402600001 | - |
dc.identifier.bibliographicCitation | European Radiology, v.33, no.3, pp 1963 - 1972 | - |
dc.citation.title | European Radiology | - |
dc.citation.volume | 33 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 1963 | - |
dc.citation.endPage | 1972 | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | DUAL-ENERGY | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | LONG-TERM | - |
dc.subject.keywordPlus | IMPLANTATION | - |
dc.subject.keywordPlus | STENOSIS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordAuthor | Aortic valve stenosis | - |
dc.subject.keywordAuthor | Computed tomography | - |
dc.subject.keywordAuthor | Aortic valve | - |
dc.subject.keywordAuthor | Calcification | - |
dc.subject.keywordAuthor | Transcatheter aortic valve replacement | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.