Association between metabolic syndrome and mortality in patients with COVID-19: A nationwide cohort study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Hyo Jin | - |
dc.contributor.author | Jung, Jin-Hyung | - |
dc.contributor.author | Han, Kyungdo | - |
dc.contributor.author | Shin, Jean | - |
dc.contributor.author | Lee, Yoojeong | - |
dc.contributor.author | Chang, Yujin | - |
dc.contributor.author | Park, Kyeyeung | - |
dc.contributor.author | Cho, Yoon Jeong | - |
dc.contributor.author | Choi, Youn Seon | - |
dc.contributor.author | Kim, Seon Mee | - |
dc.contributor.author | Nam, Ga Eun | - |
dc.date.accessioned | 2023-02-02T01:40:08Z | - |
dc.date.available | 2023-02-02T01:40:08Z | - |
dc.date.issued | 2022-11 | - |
dc.identifier.issn | 1871-403X | - |
dc.identifier.issn | 1878-0318 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/62319 | - |
dc.description.abstract | Objectives We investigated the association between metabolic syndrome (MetS) and mortality among coronavirus disease 2019 (COVID-19) patients in Korea. Methods We analyzed 3876 individuals aged ≥ 20 years who were confirmed with COVID-19 from January 1 to June 4, 2020 based on the Korea National Health Insurance Service (NHIS)-COVID-19 database and had undergone health examination by NHIS between 2015 and 2017. Multivariable Cox proportional hazard regression analyses were performed. Results Of total participants, the prevalence of MetS was 21.0% (n = 815). During 58.6 days of mean follow-up, 3.1 % (n = 120) of the participants died. Compared to individuals without MetS, COVID-19 patients with MetS had a significantly increased mortality risk after adjusting for confounders in total participants (hazard ratio [HR]: 1.68, 95 % confidence interval [CI]: 1.14–2.47) and women (HR: 2.41, 95 % CI: 1.17–4.96). A low high-density lipoprotein cholesterol level in total participants (HR: 1.63, 95 % CI: 1.12–2.37) and hyperglycemia in women (HR: 1.97, 95 % CI: 1.01–3.84) was associated with higher mortality risk. The mortality risk increased as the number of MetS components increased among total participants and women (P for trend = 0.009 and 0.016, respectively). In addition, MetS groups had higher mortality risk in aged ≥ 60 years (HR: 1.60, 95 % CI: 1.07–2.39), and never-smokers (2.08, 1.21–3.59). Conclusions The presence of MetS and greater number of its components were associated with increased mortality risks particularly in female patients with COVID-19. Managing MetS may contribute to better outcomes of COVID-19. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | Association between metabolic syndrome and mortality in patients with COVID-19: A nationwide cohort study | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1016/j.orcp.2022.10.011 | - |
dc.identifier.scopusid | 2-s2.0-85143379862 | - |
dc.identifier.wosid | 000899801000007 | - |
dc.identifier.bibliographicCitation | Obesity Research and Clinical Practice, v.16, no.6, pp 484 - 490 | - |
dc.citation.title | Obesity Research and Clinical Practice | - |
dc.citation.volume | 16 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 484 | - |
dc.citation.endPage | 490 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | COMORBIDITIES | - |
dc.subject.keywordAuthor | Metabolic syndrome | - |
dc.subject.keywordAuthor | COVID-19 | - |
dc.subject.keywordAuthor | SARS-CoV-2 | - |
dc.subject.keywordAuthor | Mortality | - |
dc.subject.keywordAuthor | Women | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.