Retrospective Multicenter Analysis of Prognostic Risk Factors for One Year Recurrence in Patient With Renal Cell Carcinoma After Partial or Radical Nephrectomy: Results of Korean Renal Cancer Study Group (KRoCS) Database
DC Field | Value | Language |
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dc.contributor.author | Choi, Changil | - |
dc.contributor.author | Kang, Minyong | - |
dc.contributor.author | Seo, Seong Il | - |
dc.contributor.author | Suh, Jungyo | - |
dc.contributor.author | Song, Cheryn | - |
dc.contributor.author | Chung, Jinsoo | - |
dc.contributor.author | Kim, Sung Han | - |
dc.contributor.author | Park, Jae Young | - |
dc.contributor.author | Hwang, Eu Chang | - |
dc.contributor.author | Jeong, Chang Wook | - |
dc.contributor.author | Kwak, Cheol | - |
dc.contributor.author | Kim, Jung Kwon | - |
dc.contributor.author | Hong, Sung-Hoo | - |
dc.date.accessioned | 2024-02-06T07:30:12Z | - |
dc.date.available | 2024-02-06T07:30:12Z | - |
dc.date.issued | 2024-01 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/65404 | - |
dc.description.abstract | BACKGROUND: We sought to identify prognostic risk factors for one year recurrence in patient with renal cell carcinoma (RCC) after partial or radical nephrectomy. METHODS: We performed a retrospective study of 1,269 patients with RCC after partial or radical nephrectomy and diagnosed recurrence using Korean Renal Cancer Study Group (KRoCS) database between January 1991 and March 2017. Recurrence-free survival (RFS), and overall survival (OS) were calculated using the Kaplan-Meier method and multivariate Cox regression analysis were performed to evaluate independent prognostic factors for recurrence. RESULTS: The median patient age was 56 years and median follow-up period was 67 months. Multivariable analysis demonstrated BMI greater than or equal to 23 and less than 30 (vs. BMI less than 23, hazard ratio [HR]: 0.707, P = 0.020) reduced recurrence one year postoperatively. Eastern Cooperative Oncology Group performance status (ECOG PS) greater than or equal to 1 (vs. ECOG PS 0, HR: 1.548, P = 0.007), high pathological T stage (pT2 vs. pT1, HR: 2.622, P < 0.001; pT3 vs. pT1, HR: 4.256, P < 0.001; pT4 vs. pT1, HR: 4.558, P < 0.001), and tumor necrosis (vs. no tumor necrosis, HR: 2.822, P < 0.001) were independent predictive factors for early recurrence within one year in patients with RCC. Statistically significant differences on RFS and OS were found among pathological T stages (pT2 vs. pT1; pT3 vs. pT1; pT4 vs. pT1, all P < 0.001). CONCLUSION: This large multicenter study demonstrated ECOG PS greater than or equal to 1, high pathological T stage, tumor necrosis and BMI less than 23 were significant prognostic risk factors of early recurrence within one year in patients with RCC who underwent nephrectomy. © 2024 The Korean Academy of Medical Sciences. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한의학회 | - |
dc.title | Retrospective Multicenter Analysis of Prognostic Risk Factors for One Year Recurrence in Patient With Renal Cell Carcinoma After Partial or Radical Nephrectomy: Results of Korean Renal Cancer Study Group (KRoCS) Database | - |
dc.title.alternative | Retrospective Multicenter Analysis of Prognostic Risk Factors for One Year Recurrence in Patient With Renal Cell Carcinoma After Partial or Radical Nephrectomy: Results of Korean Renal Cancer Study Group (KRoCS) Database | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3346/jkms.2024.39.e11 | - |
dc.identifier.scopusid | 2-s2.0-85183275018 | - |
dc.identifier.wosid | 001165994500007 | - |
dc.identifier.bibliographicCitation | Journal of Korean Medical Science, v.39, no.3, pp e11 - 9 | - |
dc.citation.title | Journal of Korean Medical Science | - |
dc.citation.volume | 39 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | e11 | - |
dc.citation.endPage | 9 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART003046031 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | PREDICT | - |
dc.subject.keywordPlus | TRIAL | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordAuthor | Early Metastasis | - |
dc.subject.keywordAuthor | Prognosis | - |
dc.subject.keywordAuthor | Recurrence | - |
dc.subject.keywordAuthor | Renal Cell Carcinoma | - |
dc.subject.keywordAuthor | Risk Factor | - |
dc.subject.keywordAuthor | Survival | - |
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