Is There a Difference in the Incidence of Depression between Radiation and Surgical Treatments in Patients with Prostate Cancer?
DC Field | Value | Language |
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dc.contributor.author | Tae, Bum Sik | - |
dc.contributor.author | Ahn, Sun Tae | - |
dc.contributor.author | Yoo, Jung Wan | - |
dc.contributor.author | Song, Min Sung | - |
dc.contributor.author | Choi, Hoon | - |
dc.contributor.author | Bae, Jae Hyun | - |
dc.contributor.author | Park, Jae Young | - |
dc.date.accessioned | 2024-02-13T03:00:07Z | - |
dc.date.available | 2024-02-13T03:00:07Z | - |
dc.date.issued | 2024-01 | - |
dc.identifier.issn | 2287-4208 | - |
dc.identifier.issn | 2287-4690 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/65417 | - |
dc.description.abstract | Purpose: Patients with cancer have a high risk of depression. However, a few studies have assessed differences in the inci-dence of depression among patients with prostate cancer (PC) based on whether they received radiotherapy (RTx) or surgical treatment.Materials and Methods: We analyzed data from the National Health Insurance Sharing Service database regarding the entire Korean adult population with PC (n=210,924) between 2007 and 2017. The adjusted hazard ratios (HRs) of depression as-sociated with treatment were estimated using propensity score-matched Cox proportional hazards models and Kaplan-Meier survival analyses.Results: Our final cohort comprised 9,456 patients with PC; of which, 8,050 men underwent surgery. During a mean follow-up duration of 7.1 years, 503 (5.3%) patients were newly diagnosed with depression. A significant difference in the incidence of depression was noted between the RTx and surgery groups (RTx vs. surgery: 5.55% vs. 5.28%; p=0.011) in the unmatched cohort. In the matched cohort, older age (>= 70 years, HR: 1.596, p<0.001) and poor Charlson comorbidity index scores (HR: 1.232, p=0.039) were correlated with the risk of depression. In addition, the adjusted HR for depression in the surgery group was 0.843 (p=0.221) compared with that in the RTx group. Kaplan-Meier analyses revealed that no significant difference in the cumulative probability of persistent depression was detected between the RTx and surgery groups in matched cohort (p=0.3386).Conclusions: In this nationwide population-based study, no significant differences in the risk of depression were observed between the surgical and RTx groups. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한남성과학회 | - |
dc.title | Is There a Difference in the Incidence of Depression between Radiation and Surgical Treatments in Patients with Prostate Cancer? | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.5534/wjmh.230119 | - |
dc.identifier.wosid | 001138640000007 | - |
dc.identifier.bibliographicCitation | The World Journal of Men's Health, v.42, no.1, pp 237 - 244 | - |
dc.citation.title | The World Journal of Men's Health | - |
dc.citation.volume | 42 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 237 | - |
dc.citation.endPage | 244 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART003025879 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | Health Care Sciences & Services | - |
dc.relation.journalResearchArea | Urology & Nephrology | - |
dc.relation.journalWebOfScienceCategory | Andrology | - |
dc.relation.journalWebOfScienceCategory | Health Care Sciences & Services | - |
dc.relation.journalWebOfScienceCategory | Urology & Nephrology | - |
dc.subject.keywordPlus | QUALITY-OF-LIFE | - |
dc.subject.keywordPlus | ACTIVE SURVEILLANCE | - |
dc.subject.keywordPlus | SURVIVORS | - |
dc.subject.keywordPlus | REGRET | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordAuthor | Depression | - |
dc.subject.keywordAuthor | Prostatic neoplasms | - |
dc.subject.keywordAuthor | Surgery | - |
dc.subject.keywordAuthor | Radiotherapy | - |
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