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Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome
- Authors
- Oh, Mi Mi; Ham, Byeong Kuk; Kang, Seok Ho; Bae, Jae Hyun; Kim, Je Jong; Yoo, Ki Hwan; Yoon, Duck Ki; Moon, Du Geon
- Issue Date
- Oct-2011
- Publisher
- SPRINGER
- Keywords
- Lesch-Nyhan syndrome; Urine alkalinization; Stones
- Citation
- UROLOGICAL RESEARCH, v.39, no.5, pp 417 - 419
- Pages
- 3
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- UROLOGICAL RESEARCH
- Volume
- 39
- Number
- 5
- Start Page
- 417
- End Page
- 419
- ISSN
- 0300-5623
1434-0879
- Abstract
- Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.
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Related Researcher
- Kim, Je Jong
- Anam Hospital (Department of Urology, Anam Hospital)