Clinical implications of multidrug-resistant microorganisms and fungi isolated from patients with intra-abdominal infections in the Republic of Korea: A multicenter study
- Authors
- Yoon, Young Kyung; Yang, Kyung Sook; Kim, Jieun; Moon, Chisook; Lee, Mi Suk; Hur, Jian; Kim, Jeong Yeon; Kim, Shin-Woo
- Issue Date
- Jul-2021
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Candida; Enterococcus; Intra-abdominal infections; Mortality; Multidrug-resistance
- Citation
- DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, v.100, no.3
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Volume
- 100
- Number
- 3
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/1319
- DOI
- 10.1016/j.diagmicrobio.2019.114960
- ISSN
- 0732-8893
1879-0070
- Abstract
- The purpose of this study was to evaluate the clinical significance of fungi and multidrug-resistant organisms (MDROs) isolated from patients with intra-abdominal infections (IAIs). This multicenter study included consecutive patients admitted for microbiologically proven IAIs at 6 university-affiliated hospitals in South Korea between 2016 and 2018.
A total of 1571 patients were enrolled. Multivariable logistic regression analysis revealed that the isolation of MDROs, isolation of Candida spp., underlying renal diseases, Charlson comorbidity score >= 3, septic shock, failure to receive a required surgery or invasive intervention, secondary bacteremia due to IAIs, and lower body mass index were found to be independent predictors for 2 8-day mortality. However, the isolation of Enterococcus spp. was not identified as a significant risk factor. MDROs and Candida spp. were found in 42 (2.7 %) and 395 (25.1%), patients respectively. The isolation of MDROs or Candida spp. was a surrogate marker of 28-day mortality.
(c) 2019 Published by Elsevier Inc.
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Collections - 5. Others > Medical Science Research Management Center > 1. Journal Articles
- 2. Clinical Science > Department of Infectious Diseases > 1. Journal Articles
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