Increased responsiveness may be associated with tripronuclear embryos in both conventional in vitro fertilization and intracytoplasmic sperm injection cycles using gonadotropin-releasing hormone agonist long protocols: A self-matched observational study
- Authors
- Jin Kim Y.; Ku S.-Y.; Jee B.C.; Suh C.S.; Kim S.H.; Choi Y.M.; Kim J.G.; Moon S.Y.
- Issue Date
- Jan-2011
- Publisher
- WILEY
- Keywords
- Conventional in vitro fertilization (IVF); Intracytoplasmic sperm injection (ICSI); Tripronuclear (3PN) embryos
- Citation
- Journal of Obstetrics and Gynaecology Research, v.37, no.1, pp 37 - 44
- Pages
- 8
- Indexed
- SCIE
SCOPUS
- Journal Title
- Journal of Obstetrics and Gynaecology Research
- Volume
- 37
- Number
- 1
- Start Page
- 37
- End Page
- 44
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14036
- DOI
- 10.1111/j.1447-0756.2010.01313.x
- ISSN
- 1341-8076
1447-0756
- Abstract
- Aims: In this self-matched observational study, the factors associated with the presence of tripronuclear (3PN) embryos, in conventional in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cycles using gonadotropin-releasing hormone agonist long protocols, were investigated. Material & Methods: Clinical parameters were analyzed in 202 consecutive IVF-IVF or ICSI-ICSI matched cycles. The differences between the former and latter cycles were evaluated and compared according to the presence of 3PN embryos: group A [3PN (-) followed by 3PN (-)]; group B [3PN (-) followed by 3PN (+)]; group C [3PN (+) followed by 3PN (-)]; group D [3PN (+) followed by 3PN (+)]. Results: For the IVF-IVF cycles, the E 2 on human chorionic gonadotropin injection day and the number of retrieved oocytes were increased in the 3PN (+) cycles compared to the 3PN (-) cycles of Groups B (2165.2 ± 1423.3 pg/mL vs 1468.2 ± 796.2 pg/mL, P = 0.016; 10.4 ± 9.1 vs 7.2 ± 5.7, P = 0.010) and C (2382.7 ± 1214.5 pg/mL vs 1553.0 ± 1119.6 pg/mL, P = 0.004; 13.1 ± 9.1 vs 9.1 ± 7.0, P < 0.001), while these outcome variables did not differ when the former and latter cycles in Groups A and D were compared. These trends were observed in the ICSI-ICSI cycles. Conclusions: An increased responsiveness, based on the higher E 2 and greater number of retrieved oocytes, may be associated with the presence of 3PN in both conventional IVF and ICSI cycles. © 2010 Japan Society of Obstetrics and Gynecology.
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Collections - 2. Clinical Science > Department of Obstetrics and Gynecology > 1. Journal Articles
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