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Skin absorption potential of ZnO nanoparticles
- Authors
- Kim S.Y.; Jeong S.H.; Lee E.Y.; Park Y.-H.; Bae H.C.; Jang Y.S.; Maeng E.H.; Kim M.-K.; Son S.W.
- Issue Date
- 2011
- Publisher
- Kluwer Academic Publishers
- Keywords
- 3D EpiDerm™ model (EPI-200); Absorption; Skin; ZnO
- Citation
- Toxicology and Environmental Health Sciences, v.3, no.4, pp 258 - 261
- Pages
- 4
- Indexed
- SCOPUS
- Journal Title
- Toxicology and Environmental Health Sciences
- Volume
- 3
- Number
- 4
- Start Page
- 258
- End Page
- 261
- ISSN
- 2005-9752
- Abstract
- In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure. © 2011 Korean Society of Environmental Risk Assessment and Health Science and Springer.
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Related Researcher
- Son, Sang Wook
- Ansan Hospital (Department of Dermatology, Ansan Hospital)