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Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
- Authors
- Cho, Eunjung; Cha, Inhye; Yoon, Kichul; Yang, Ha Na; Kim, Hye Won; Kim, Myung-Gyu; Jo, Sang-Kyung; Cho, Won Yong; Kim, Hyoung Kyu
- Issue Date
- Oct-2010
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- Acute Hepatitis A; Acute Kidney Injury; Lymphohistiocytosis, Hemophagocytic
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.25, no.10, pp 1529 - 1531
- Pages
- 3
- Indexed
- SCI
SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 25
- Number
- 10
- Start Page
- 1529
- End Page
- 1531
- ISSN
- 1011-8934
1598-6357
- Abstract
- Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by virus-associated hemophagocytic syndrome (VAHS). Our patient, a 48-yr-old man, was diagnosed with HAV infection complicated by dialysis-dependent AKI. His kidney biopsy showed acute tubulointerstitial nephritis with massive infiltration of activated macrophages and T cells, and he progressively demonstrated features of VAHS. With hemodialysis and steroid treatment, he was successfully recovered.
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Related Researcher
- Cho, Won Yong
- Anam Hospital (Department of Nephrology and Hypertension, Anam Hospital)