Detailed Information

Cited 55 time in webofscience Cited 64 time in scopus
Metadata Downloads

Safety and Convenience of Continuous Warfarin Strategy During the Periprocedural Period in Patients Who Underwent Catheter Ablation of Atrial Fibrillation

Authors
Kwak, Jae-JinPak, Hui-NamJang, Jin-KunKim, Sook KyoungPark, Jae HyungChoi, Jong-IlHwang, ChunKim, Young-Hoon
Issue Date
Jun-2010
Publisher
WILEY
Keywords
anticoagulation; atrial fibrillation; warfarin; heparin; catheter ablation
Citation
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, v.21, no.6, pp.620 - 625
Indexed
SCIE
SCOPUS
Journal Title
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
Volume
21
Number
6
Start Page
620
End Page
625
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14831
DOI
10.1111/j.1540-8167.2009.01670.x
ISSN
1045-3873
Abstract
Methods and Results: We compared CW (n = 49) and SH (n = 55, 3 days before RFCA) in 104 patients who underwent RFCA of AF (77 males, 55 +/- 12 years old, paroxysmal AF: persistent AF = 63:41). During the procedure, the activated clotting time (ACT) was maintained between 350 and 400 seconds, and a requirement of H, postablation INR, and periprocedural complications were compared. Results were as follows: (1) in the CW group, the preprocedural INR (1.85 +/- 0.61 vs 1.05 +/- 0.12, P < 0.001) and the proportions of INR > 2.0 after RFCA (1st postprocedure day 61.2% vs 5.5%, P < 0.001; 2nd postprocedure day 83.3% vs 21.8%, P < 0.005) were higher, and the heparin requirement was lower (2012 +/- 998 U/30 minutes vs 2921 +/- 795 U/30 minutes, P < 0.001) than in the SH group. (2) The incidences of hemorrhagic complications (18.2% vs 18.4%, P = NS) or the major bleeding rates (reduced hemoglobin >= 4 g/dL, requiring blood transfusion; 3.6% vs 12.2%, P = NS) were not significantly different in the CW group than in the SH group. Conclusion: The periprocedural CW strategy maintains a more stable INR immediately after AF ablation without increasing hemorrhagic complications compared with the classic strategy of SH. Simple CW can replace SH in an experienced laboratory with a low risk of hemopericardium during AF ablation. (J Cardiovasc Electrophysiol, Vol. 21, pp. 620-625, June 2010).
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Cardiology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Choi, Jong il photo

Choi, Jong il
Anam Hospital (Department of Cardiology, Anam Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE