Clinical courses after administration of oral corticosteroids in patients with severely cholestatic acute hepatitis A; three cases.
- Authors
- Yoon E.L.; Yim H.J.; Kim S.Y.; Kim J.H.; Lee J.H.; Lee Y.S.; Lee H.J.; Jung S.W.; Lee S.W.; Choi J.H.
- Issue Date
- 2010
- Keywords
- Acute hepatitis A; Cholestasis; Corticosteroid; Acute hepatitis A; Cholestasis; Corticosteroid
- Citation
- The Korean journal of hepatology, v.16, no.3, pp 329 - 333
- Pages
- 5
- Indexed
- SCOPUS
KCI
- Journal Title
- The Korean journal of hepatology
- Volume
- 16
- Number
- 3
- Start Page
- 329
- End Page
- 333
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/15418
- DOI
- 10.3350/kjhep.2010.16.3.329
- ISSN
- 1738-222X
- Abstract
- Acute hepatitis A is currently outbreaking in Korea. Although prognosis of acute hepatitis A is generally favorable, a minority of patients are accompanied by fatal complications. Severe cholestasis is one of the important causes of prolonged hospitalization in patients with acute hepatitis A. In such cases, higher chances of additional complications and increased medical costs are inevitable. We report three cases of severely cholestatic hepatitis A, who showed favorable responses to oral corticosteroids. Thirty milligram of prednisolone was initiated and tapered according to the responses. Rapid improvement was observed in all cases without side effects. We suggest that corticosteroid administration can be useful in hepatitis A patients with severe cholestasis who do not show improvement by conservative managements. Clinical trial will be needed to evaluate effectiveness of corticosteroids in these patients.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 2. Clinical Science > Department of Pathology > 1. Journal Articles
- 2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.