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Clinical Features and Survival Outcomes in Patients with Multiple Myeloma: Analysis of Web-Based Data from the Korean Myeloma Registry
- Authors
- Kim, Seok Jin; Kim, Kihyun; Kim, Byung Soo; Jo, Deog-Yeon; Kang, Hye Jin; Kim, Jin Seok; Mun, Yeung-Chul; Kim, Chul Soo; Sohn, Sang Kyun; Eom, Hyeon-Seok; Kwak, Jae-Yong; Shim, Hyeok; Yoon, Hwi-Joong; Jin, Jong-Youl; Min, Chang-Ki; Shin, Hyunchoon; Won, Jong-Ho; Lee, Je-Jung; Kwon, Jung Hye; Joo, Young-Don; Do, Young Rok; Kim, Sung-Hyun; Oh, Sukjoong; Suh, Cheolwon; Lee, Junglim; Yoon, Sung-Soo; Kim, Min Kyoung; Bang, Soo-Mee; Ryoo, Hun-Mo; Kim, Bong-Seog; Kim, Hawk; Kim, Hyo Jung; Kim, Yang Soo; Park, Chong Won; Lee, Gyeong-Won; Shin, Ho Jin; Park, Seong Kyu; Park, Joon Seong; Kim, Ho Young; Lee, Dong Soon; Lee, Jae Hoon
- Issue Date
- 2009
- Publisher
- KARGER
- Keywords
- Multiple myeloma; Stem cell transplantation, autologous; Stem cell transplantation, tandem autologous
- Citation
- ACTA HAEMATOLOGICA, v.122, no.4, pp 200 - 210
- Pages
- 11
- Indexed
- SCIE
SCOPUS
- Journal Title
- ACTA HAEMATOLOGICA
- Volume
- 122
- Number
- 4
- Start Page
- 200
- End Page
- 210
- ISSN
- 0001-5792
1421-9662
- Abstract
- Aim: The Korean Multiple Myeloma Working Party performed a nationwide registration of multiple myeloma patients via a web-based data bank system. Methods: We retrospectively analyzed registered data from 3,209 patients since 1999. Results: The median overall survival (OS) was 50.13 months (95% confidence interval: 46.20-54.06 months). Patients <= 40 years demonstrated a longer OS than patients >65 years of age (median OS 71.13 vs. 36.73 months, p < 0.001). Patients who received novel agents at any time during their treatments showed a longer OS than patients who did not (median OS 42.23 vs. 55.50 months, p < 0.001). Response to treatment was associated with OS, with tandem autologous stem cell transplantation (SCT) producing longer OS than single autologous SCT. Conclusions: We demonstrated associations between survival outcomes and treatment modalities as well as baseline disease characteristics in a registry of multiple myeloma patients using a web-based data analysis. Copyright (C) 2009 S. Karger AG, Basel
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Related Researcher
- Kim, Byung Soo
- Anam Hospital (Department of Medical Oncology and Hematology, Anam Hospital)