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Cited 13 time in webofscience Cited 17 time in scopus
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Radiotherapy for 65 patients with advanced unresectable hepatocellular carcinomaopen access

Authors
Seo, Yeon SeokKim, Jin NamKeum, BoraPark, SanghoonKwon, Yong DaeKim, Yong SikJeen, Yoon TaeChun, Hoon JaiKim, Chul YongKim, Chang DuckRyu, Ho SangUm, Soon Ho
Issue Date
Apr-2008
Publisher
BAISHIDENG PUBLISHING GROUP INC
Keywords
hepatocellular carcinoma; radiotherapy; treatment response; survival
Citation
WORLD JOURNAL OF GASTROENTEROLOGY, v.14, no.15, pp.2394 - 2400
Indexed
SCIE
SCOPUS
Journal Title
WORLD JOURNAL OF GASTROENTEROLOGY
Volume
14
Number
15
Start Page
2394
End Page
2400
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/17042
DOI
10.3748/wjg.14.2394
ISSN
1007-9327
Abstract
AIM: To evaluate the efficacy of radiotherapy (RT) in patients with advanced unresectable hepatocellular carcinoma (HCC). METHODS: A total of 65 patients were treated with RT in the Korea University Medical Center. The median age of the patients was 60 years, and 86.2% were men. 18.5% and 81.5% of the patients were diagnosed as TNM stage M and IV-A, respectively. Treatment response was assessed 4 mo after initiation of RT. Tumor regression rate I mo after initiation of RT (TRR1m) was also assessed. Duration of survival was calculated from the initiation of RT. RESULTS: The objective treatment response was 56.9%. The 12 mo survival rate was 34.7%. Predictive factors for survival were Child-Pugh grade, alpha-fetoprotein level and treatment response. An objective response was achieved more frequently in patients with TRR1m >= 20% than in those with TRR1m < 20% (P < 0.001). CONCLUSION: RT is effective in treating advanced HCC with a tumor response rate of 56.9%. (c) 2008 WJG. All rights reserved.
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2. Clinical Science > Department of Internal Medicine > 1. Journal Articles
5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Radiation Oncology > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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Jeen, Yoon Tae
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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