Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional studyopen access
- Authors
- Lee, Tae Hyub; Song, Gwan Gyu; Choi, Sung Jae; Seok, Hongdeok; Jung, Jae Hyun
- Issue Date
- Aug-2019
- Keywords
- Rheumatoid arthritis; Prevalence; Angina pectoris; Myocardial infarction
- Citation
- Advances in rheumatology, v.59, no.1
- Indexed
- SCIE
SCOPUS
- Journal Title
- Advances in rheumatology
- Volume
- 59
- Number
- 1
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/1719
- DOI
- 10.1186/s42358-019-0084-6
- ISSN
- 2523-3106
- Abstract
- Background Rheumatoid arthritis (RA) is known to be associated with coronary artery diseases (CAD). Previous studies of the association between RA and CAD were reported mainly in non-Asian groups. We aimed to examine the prevalence of RA and the relationship between RA and CAD in South Korea. Methods We conducted a nationwide cross-sectional study by using the Korea National Health and Nutrition Examination Survey, which collected data for four years between 2008 and 2012. A total of 25,828 eligible participants were included. To balance the distribution of baseline characteristics, we used propensity score-matching. A multivariable logistic regression model was employed and we calculated the odds ratios (ORs) and 95% confidence intervals (CI) for the odds of the participants with RA on CAD prevalence. Results The prevalence of RA in Korea from 2008 to 2012 was 0.6% and RA was predominant among elderly women. The prevalence of CAD in patients with RA was significantly higher than in general population. After propensity score-matching to balance the confounding factors, RA was significantly associated with CAD (OR 2.97, 95% CI 1.15-7.68, P = 0.02). Conclusions The prevalence of RA in South Korea was comparable to the worldwide data, and the presence of CAD in RA patients was more than two-fold.
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Collections - 2. Clinical Science > Department of Rheumatology > 1. Journal Articles
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