Development and psychometric evaluation of a chronic liver disease-specific quality of life questionnaire
- Authors
- Lee, Eun-Hyun; Cheong, Jae Youn; Cho, Sung Won; Hahm, Ki-Baik; Kim, Hak Yang; Park, Jong-Jae; Lee, Dong Ho; Kim, Seong Kook; Choi, Seok Reyol; Lee, Soo Teik; Moon, Seong Mi
- Issue Date
- Feb-2008
- Publisher
- WILEY
- Keywords
- chronic liver disease; health-related quality of life; reliability; validity
- Citation
- JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, v.23, no.2, pp 231 - 238
- Pages
- 8
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Volume
- 23
- Number
- 2
- Start Page
- 231
- End Page
- 238
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/17194
- DOI
- 10.1111/j.1440-1746.2007.05034.x
- ISSN
- 0815-9319
1440-1746
- Abstract
- Background and Aims: There has been no reliable and valid instrument to measure health-related quality of life for Asian patients with chronic liver disease. The aim of the present study was to develop and evaluate a chronic liver disease-specific quality of life (CLD-QOL) questionnaire for Korean patients with chronic liver disease. Methods: Content-validated items were evaluated psychometrically in 271 patients with chronic liver disease recruited from seven university hospitals in Korea. The participants were asked to complete a preliminary questionnaire comprising the content-validated items and the Short Form-36 Health Survey. The Child-Pugh classification was used to classify the severity of liver cirrhosis. Results: Factor analysis extracted a five-factor solution from 27 preliminary items, which were generated by an expert panel and a pilot study, but factor and a multidimensional scaling analysis revealed that four items were not loaded significantly on any factor, suggesting that the four items might be heterogeneous. After deletion of these four items, a multiscaling analysis strongly supported item convergence and discriminant validity. The CLD-QOL was associated significantly with the Child-Pugh classification and the type of patient status (inpatient/outpatient) and was moderately correlated with the subscales of the Short Form-36 Health Survey. The values of Cronbach's alpha for the subscales of the novel CLD-QOL questionnaire were all greater than 0.70. Conclusions: The novel CLD-QOL questionnaire we developed is an easily applicable tool that exhibits excellent psychometric properties for Korean patients with chronic liver disease. It is recommended for the CLD-QOL to apply for Asian patients with chronic liver disease.
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- Appears in
Collections - 2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles
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