Detailed Information

Cited 52 time in webofscience Cited 62 time in scopus
Metadata Downloads

Comparison of postpolypectomy bleeding between epinephrine and saline submucosal injection for large colon polyps by conventional polypectomy: A prospective randomized, multicenter studyopen access

Authors
Lee, Suck-HoChung, Il-KwunKim, Sun-JooKim, Jin-OhKo, Bong-MinKim, Won HoKim, Hyun-SooPark, Dong-IlKim, Hyo-JongByeon, Jeong-SikYang, Suk-KyunJang, Byeong IkJung, Sung-AeJeen, Yoon-TaeChoi, Jai-HyunChoi, HwangHan, Dong-SooSong, Jae Suk
Issue Date
7-Jun-2007
Publisher
BAISHIDENG PUBLISHING GROUP INC
Keywords
colonoscopic polypectomy; bleeding; submucosal injection; saline; epinephrine
Citation
WORLD JOURNAL OF GASTROENTEROLOGY, v.13, no.21, pp.2973 - 2977
Indexed
SCIE
SCOPUS
Journal Title
WORLD JOURNAL OF GASTROENTEROLOGY
Volume
13
Number
21
Start Page
2973
End Page
2977
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/17896
DOI
10.3748/wjg.v13.i21.2973
ISSN
1007-9327
Abstract
AIM: To evaluate and compare the clinical outcomes of prophylactic submucosal saline-epinephrine injection and saline injection alone for large colon polyps by conventional polypectomy. METHODS: A prospective study was conducted from July 2003 to July 2004 at 11 tertiary endoscopic centers. Large colon polyps (> 10 mm in diameter) were randomized to undergo endoscopic polypectomy with submucosal saline-epinephrine injection (epinephrine group) or normal saline injection (saline group). Endoscopic polypectomy was performed by the conventional snare method, and early (< 12 h) and late bleeding complications (12 h-30 d) were observed. RESULTS: A total of 561 polyps in 486 patients were resected by endoscopic polypectomy. Overall, bleeding complications occurred in 7.6% (37/486) of the patients, including 4.9% (12/244) in the epinephrine group, and 10.3% (25/242) in the saline group. Early and late postpolypectomy bleeding (PPB) occurred in 6.6% (32/486) and 1% (5/486) of the patients, respectively, including 4.5% (11/244), 0.4% (1/244) in the epinephrine group, and 8.7% (21/242), 1.7% (4/242) in the saline group. No significant differences in the rates of overall, early and late PPB were observed between the 2 groups. Multivariate stepwise logistic regression analysis revealed that large size (> 2 cm) and neoplastic polyps were independently and significantly associated with the presence of PPB. CONCLUSION: The prophylactic submucosal injection of diluted epinephrine does not appear to provide an additional advantage over the saline injection alone for the prevention of PPB. (C) 2007 The WJG Press. All rights reserved.
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Jeen, Yoon Tae photo

Jeen, Yoon Tae
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE