Neurologic complications in adult living donor liver transplant recipients
- Authors
- Kim B.-S.; Lee S.-G.; Hwang S.; Park K.-M.; Kim K.-H.; Ahn C.-S.; Moon D.-B.; Ha T.-Y.; Song G.-W.; Kim D.-S.; Moon K.-M.; Jung D.-H.
- Issue Date
- Jul-2007
- Publisher
- BLACKWELL PUBLISHING
- Keywords
- Complication; Liver transplantation; Neurologic
- Citation
- Clinical Transplantation, v.21, no.4, pp 544 - 547
- Pages
- 4
- Indexed
- SCOPUS
- Journal Title
- Clinical Transplantation
- Volume
- 21
- Number
- 4
- Start Page
- 544
- End Page
- 547
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/18403
- DOI
- 10.1111/j.1399-0012.2007.00687.x
- ISSN
- 0902-0063
1399-0012
- Abstract
- Background: Neurologic complications (NC) after liver transplantation are not uncommon, with serious complications such as central pontine myelinolysis (CPM), often causing disability. Objective: We investigated the incidence and features of NC following liver transplantation in adult recipients. Patients and methods: We retrospectively reviewed the medical records of 319 adult patients who underwent liver transplantation between January 2004 and May 2005 at the Asan Medical Center. Results: Neurologic complications developed in 49 of 319 patients (15.4%). Although most of these complications were minor, including tremor and foot drop, three patients developed CPM, and one each developed posterior leukoencephalopathy, cerebral hemorrhage, and cerebral infarction. One-yr survival rates were 95.9% in patients without NC and 83.7% in patients with NC (p = 0.004). Hospital stay was prolonged in patients with NC. Graft-to-recipient body weight ratio (GRWR) did not affect occurrence of NC. Conclusions: Neurologic complications were not uncommon in liver transplant recipients. These complications contributed to prolongation of hospital stay, increased in-hospital mortality, and decreased graft and patient survival. Every effort should be made to prevent NC, as well as to detect and treat them as soon as possible. © 2007 Blackwell Munksgaard.
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Collections - 2. Clinical Science > Department of Hepato-Biliary-Pancreatic Surgery > 1. Journal Articles
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