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Induction of CITED2 expression in the rat hippocampus following transient global ischemia
- Issue Date
- 9-Feb-2006
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- CITED2; HIF-1; transient forebrain ischemia; gene expression; dentate gyrus
- Citation
- BRAIN RESEARCH, v.1072, no.1, pp 15 - 18
- Pages
- 4
- Indexed
- SCIE
SCOPUS
- Journal Title
- BRAIN RESEARCH
- Volume
- 1072
- Number
- 1
- Start Page
- 15
- End Page
- 18
- ISSN
- 0006-8993
1872-6240
- Abstract
- CITED2 is implicated in the modulating the activity of HIF-1 which is a major transcription factor involved in ischemia-related gene expression. Following transient forebrain ischemia, we found that CITED2 was induced in a subset of brain regions including dentate gyrus of the hippocampal formation and piriform cortex. Because CITED2 was not induced in cultured neurons exposed to oxygen-glucose deprivation, we concluded that hypoxia is not sufficient to trigger its induction. (c) 2006 Elsevier B.V. All rights reserved.
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Collections - 1. Basic Science > Department of Anatomy > 1. Journal Articles
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Related Researcher
- Sun, Woong
- College of Medicine (Department of Anatomy)