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Delayed puberty due to pituitary stalk dysgenesis and ectopic neurohypophysis

Authors
Yoo H.J.Choi K.M.Ryu O.H.Suh S.I.Kim N.H.Baik S.H.Choi D.S.
Issue Date
2006
Publisher
Korean Association of Internal Medicine
Keywords
Delayed puberty; Hypopituitarism; Neurohypophysis; Pituitary stalk
Citation
Korean Journal of Internal Medicine, v.21, no.1, pp 68 - 72
Pages
5
Indexed
SCOPUS
KCICANDI
Journal Title
Korean Journal of Internal Medicine
Volume
21
Number
1
Start Page
68
End Page
72
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/19240
DOI
10.3904/kjim.2006.21.1.68
ISSN
1226-3303
2005-6648
Abstract
Hypopituitarism is not a common cause of delayed puberty. A 22 year old man was referred to our clinic because of the absence of the development of secondary sexual characteristics. The patient had no complaints of physical discomfort. Random serum testosterone and luteinizing hormone level were obtained and found to be low. The combined pituitary function stimulation test revealed a partial hypopituitarism. A pituitary magnetic resonance imaging (MRI) was obtained and showed decreased pituitary stalk enhancement and ectopic neurohypophysis. Therefore, we conclude that the delayed puberty was a result of hypopituitarism due to pituitary stalk dysgenesis and ectopic neurohypophysis. The patient was started on hormone replacement therapy and gradually developed secondary sexual characteristics.
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2. Clinical Science > Department of Radiology > 1. Journal Articles
2. Clinical Science > Department of Endocrinology and Metabolism > 1. Journal Articles

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