Detailed Information

Cited 0 time in webofscience Cited 2 time in scopus
Metadata Downloads

A case of refractory pediatric Crohn's disease with a successful treatment by infliximab therapy

Authors
Park S.H.Jeen Y.T.Chun H.R.Kim D.I.Baeck C.W.Kim Y.S.Chun H.J.Lee H.S.Um S.H.Choi J.H.Kim C.D.Ryu H.S.Hyun J.H.
Issue Date
Oct-2005
Keywords
Crohn' s disease; Pediatrics; Infliximab
Citation
The Korean journal of gastroenterology, v.46, no.4, pp.297 - 301
Indexed
SCOPUS
KCI
Journal Title
The Korean journal of gastroenterology
Volume
46
Number
4
Start Page
297
End Page
301
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/20057
ISSN
1598-9992
Abstract
Crohn's disease is a chronic inflammatory bowel disease which affects mainly children and young adults, and its cause remains unknown so far. Infliximab, a monoclonal antibody to the pivotal cytokine tumor necrosis factor-alpha, has been approved as a drug for both induction and maintenance therapy for moderately to severely active, or fistula-complicated Crohn's disease. The authors report a 12-year-old male patient diagnosed as Crohn's disease complicated with a perianal fistula, which was refractory to the conventional therapy. After the 0, 2, and 6 week scheduled intravenous infusion of infliximab, the patient reached to clinical remission in both subjective symptoms and objective manifestations. For children or young adults who develop Crohn's disease in a refractory course, infliximab may serve as a drug which leads to a clinical improvement or even to an extent of remission.
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Internal Medicine > 1. Journal Articles
5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Chun, Hoon Jai photo

Chun, Hoon Jai
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE