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Evaluation of rapid immunocapture assays for diagnosis of Plasmodium vivax in Korea

Authors
Cho, DKim, KHPark, SCKim, YKLee, KNLim, CS
Issue Date
Jun-2001
Publisher
SPRINGER-VERLAG
Keywords
ICT; Immunocapture assay; OptiMal; Plasmodium vivax; South Korea
Citation
PARASITOLOGY RESEARCH, v.87, no.6, pp 445 - 448
Pages
4
Indexed
SCIE
SCOPUS
Journal Title
PARASITOLOGY RESEARCH
Volume
87
Number
6
Start Page
445
End Page
448
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/22515
DOI
10.1007/s004360000360
ISSN
0932-0113
1432-1955
Abstract
The rapid immunocapture assays, OptiMal and ICT, were evaluated from 87 individuals for the diagnosis of malaria infections directly from whole blood. A total of 87 individuals was examined for malaria parasites by microscopic examination of Giemsa-stained blood smears, and 65 cases were positive for Plasmodium vivax by microscopy. Correspondingly, the OptiMal test identified malaria infection in 45 cases (69.2%) of microscopy positive cases. Of these, two cases were misinterpreted as Plasmodium falciparum, whereas ICT detected P. vivax infection in 29 (44.6%) patients. We would like to propose that rapid immune capture assays are an easy method that can serve as a useful tool in addition to microscopy for the diagnosis of malaria, but sensitivity is not yet satisfactory for diagnosis of P. vivax in Korea.
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