Serum ferritin in healthy subjects and type 2 diabetic patients
- Authors
- Kim, NH; Oh, JH; Choi, KM; Kim, YH; Baik, SH; Choi, DS; Kim, SJ
- Issue Date
- Jun-2000
- Publisher
- YONSEI UNIV COLLEGE MEDICINE
- Keywords
- type 2 diabetes mellitus; insulin resistance; ferritin
- Citation
- YONSEI MEDICAL JOURNAL, v.41, no.3, pp 387 - 392
- Pages
- 6
- Indexed
- SCIE
SCOPUS
- Journal Title
- YONSEI MEDICAL JOURNAL
- Volume
- 41
- Number
- 3
- Start Page
- 387
- End Page
- 392
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/23234
- DOI
- 10.3349/ymj.2000.41.3.387
- ISSN
- 0513-5796
1976-2437
- Abstract
- In order to study the relationship between the serum ferritin level and the components of the insulin resistance syndrome in type 2 diabetic patients, we evaluated fifty type 2 diabetic patients who were selected according to NDDG/WHO criteria from those patients attending Korea University Hospital from 1997 to 1998. Twenty-five healthy non-diabetic subjects of comparable age and sex distribution acted as a control group. The results showed that the value of log ferritin was higher in the type 2 diabetes patients than the control subjects, but not at a statistically significant level (p = 0.09). Log ferritin was correlated with fasting blood sugar level (r = 0.235, p = 0.048) and body mass index (BMI) (r = 0.285, p = 0.05). In the type 2 diabetic patients, log ferritin was correlated with fasting C-peptide (r = 0.478, p = 0.009). In the control subjects, log ferritin was correlated only with BMI (r = 10.477, p = 0.012). In a stepwise multiple regression analysis, the diabetic group showed a significant correlation between fasting C-peptide and log ferritin (p = 0.001). In the control group, the fasting sugar level was significantly correlated with log ferritin (p = 0.034). These results suggest that serum ferritin can be employed as a marker of not only glucose homeostasis but also insulin resistance both in type 2 diabetic and control subjects.
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Collections - 2. Clinical Science > Department of Endocrinology and Metabolism > 1. Journal Articles
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