Usefulness of the Psoriatic Arthritis Screening and Evaluation Questionnaire to Monitor Disease Activity in Management of Patients with Psoriasis: Findings from the EPI-PSODE Study
- Authors
- Choe, Yong Beom; Park, Chul Jong; Yu, Dae Young; Kim, Youngdoe; Ju, Hyun Jeong; Youn, Sang Woong; Lee, Joo-Heung; Kim, Byung Soo; Seo, Seong Jun; Yun, Seok-Kweon; Park, Joonsoo; Kim, Nack In; Youn, Jai Il; Lee, Seok-Jong; Lee, Min-Geol; Kim, Kwang Joong; Ro, Young Suck; Song, Hae Jun; Shin, Bong Seok; Ahn, Sung Ku; Lee, Ji Yeoun; Won, Young Ho; Jang, Min Soo; Kim, Ki Ho; Kim, Myung Hwa; Kim, Tae Yoon; Choi, Jee-Ho
- Issue Date
- Feb-2019
- Publisher
- 대한피부과학회
- Keywords
- Arthritis; Psoriatic
- Citation
- Annals of Dermatology, v.31, no.1, pp 29 - 36
- Pages
- 8
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- Annals of Dermatology
- Volume
- 31
- Number
- 1
- Start Page
- 29
- End Page
- 36
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/2407
- DOI
- 10.5021/ad.2019.31.1.29
- ISSN
- 1013-9087
2005-3894
- Abstract
- Background
Psoriasis and psoriatic arthritis (PsA) are included in the group of immune-mediated inflammatory diseases (IMIDs) caused by systemic inflammation; however, indicators for monitoring inflammatory activity in patients with psoriasis, such as the Psoriasis Area and Severity Index (PASI), are limited.
Objective
To determine whether the Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire can be used to monitor disease activity in patients with psoriasis.
Methods
This was a multicenter, noninterventional, cross-sectional study. Demographic factors and PASI and PASE scores were collected to investigate associations between each.
Results
PASE data were available for 1,255 patients, of whom 498 (39.7%) had a score of ≥37. Compared with the group with PASE score <37, the group with score ≥37 had a higher proportion of women (34.9% vs. 48.8%, p<0.0001), older mean age at diagnosis (36.4 vs. 41.7 years, p<0.0001), more severe disease activity using PASI and body surface area measures (p=0.0021 and p=0.0008, respectively), and higher mean body mass index (23.7 vs. 24.1, p=0.0411). In a multiple linear regression model, PASE score was positively associated with cutaneous disease activity (p<0.0001).
Conclusion
After risk-adjustment, PASE was positively associated with PASI, which suggests that PASE can be sensitive to disease activity. Since psoriasis is regarded as one of the IMIDs, PASE may be utilized as a tool not only to screen PsA but also to monitor disease activity.
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- Appears in
Collections - 2. Clinical Science > Department of Dermatology > 1. Journal Articles
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