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Comparison of characteristics and survival between prospective and retrospective Korea human immunodeficiency virus/Acquired immune deficiency syndrome cohort studiesopen access

Authors
Kim J.H.Choi Y.Song J.Y.Kim S.-W.Kim S.I.Kee M.-K.Choi B.Y.Choi J.Y.
Issue Date
Dec-2019
Publisher
Korean Society for Antimicrobial Therapy
Keywords
Cohort study; HIV/AIDS; Survival rates
Citation
Infection and Chemotherapy, v.51, no.4, pp 393 - 398
Pages
6
Indexed
SCOPUS
ESCI
KCI
Journal Title
Infection and Chemotherapy
Volume
51
Number
4
Start Page
393
End Page
398
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/2711
DOI
10.3947/ic.2019.51.4.393
ISSN
2093-2340
2092-6448
Abstract
By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial antiretroviral treatment regimen of the prospective cohort consisted of less integrase strand transfer inhibitor-containing regimens. The 20-year survival rate was 51.8% in the prospective cohort and 84.6% in the retrospective cohort, respectively (P = 0.844). This study suggests the prospective cohort study may not represent all patients. Copyright © 2019 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS.
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Song, Joon Young
Guro Hospital (Department of Infectious Diseases, Guro Hospital)
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