급성 출혈성 백질 뇌염에서 확산텐서영상 추적검사의 유용성 증례Utility of Follow-up Diffusion Tensor Imaging in Acute Hemorrhagic Leukoencephalitis: a Case Report
- Other Titles
- Utility of Follow-up Diffusion Tensor Imaging in Acute Hemorrhagic Leukoencephalitis: a Case Report
- Authors
- 최원지; 변정혜; 은소희; 은백린; 김건하
- Issue Date
- 2017
- Publisher
- 대한소아신경학회
- Keywords
- Acute hemorrhagic leukoencephalitis; Diffusion tensor imaging; Seizure; Child
- Citation
- 대한소아신경학회지, v.25, no.1, pp 54 - 57
- Pages
- 4
- Indexed
- KCICANDI
- Journal Title
- 대한소아신경학회지
- Volume
- 25
- Number
- 1
- Start Page
- 54
- End Page
- 57
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/29576
- DOI
- 10.26815/jkcns.2017.25.1.54
- ISSN
- 1226-6884
- Abstract
- Acute hemorrhagic leukoencephalitis (AHLE) is an acute, rapidly progressing, fulminant demyelinating disease. It is a rare disease of the central nervous system with high mortality; survivors commonly present with significant neurological deficit. We report the case of a 16-month-old girl who survived AHLE and presented with the associated neurologic deficit. The patient came into the emergency department with febrile seizure. She showed bilateral pinpoint-sized pupils and hyperactive deep tendon reflexes. Her mental status was initially drowsy and rapidly progressed to stupor. Extensive demyelination and microbleeds were found in the cerebral white matter, thalamus and left cerebellum on Magnetic resonance imaging (MRI) scans. Her mental status was improved by intravenous administration of immunoglobulin and methylprednisolone. Five months after being discharged, increased white matter connectivity was found on color-coded follow-up MR diffusion tensor imaging (DTI) as compared to previous MRI. We therefore suggest adding the DTI technique when a follow-up MRI is performed in patients with AHLE. It could be useful to visualize the status of axonal injury and to encourage patients and their parents to continue the rehabilitation program.
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- Appears in
Collections - 5. Others > Others(Medicine) > 1. Journal Articles
- 2. Clinical Science > Department of Pediatrics > 1. Journal Articles
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