Discoid lupus erythematosus-like eruption induced by tegafur - Uracil (UFT)
- Authors
- Yoon J.; Seo S.-H.; Kye Y.-C.; Ahn H.H.
- Issue Date
- 2010
- Keywords
- Discoid lupus erythematosus; Tegafur; UFT
- Citation
- Korean Journal of Dermatology, v.48, no.11, pp 1004 - 1007
- Pages
- 4
- Indexed
- SCOPUS
KCI
- Journal Title
- Korean Journal of Dermatology
- Volume
- 48
- Number
- 11
- Start Page
- 1004
- End Page
- 1007
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/31131
- ISSN
- 0494-4739
- Abstract
- The second-generation oral anticancer agent UFT is a combination of uracil, which has fluorouracil's (5-FU) degradation-inhibitory effect, and tegafur, which is slowly converted to 5-FU in vivo, and UFT shows a higher 5-FU concentration in the tumor tissues than is achieved by tegafur alone or with comparable doses of intravenous 5-FU. Mucocutaneous side reactions induced by UFT are rare and these include photosensitivity of the lichenoid and eczematous types, acral erythema, hyperpigmentation, palmoplantar keratoderma and scleroderma-like reactions, and discoid lupus erythematosus (DLE)-like eruption. However, there has been no report in the Korean medical literature on patients presenting with a DLE-like eruption associated with UFT. So, we report here a case of DLE-like eruption induced by oral UFT.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 2. Clinical Science > Department of Dermatology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.