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ZD1839(Iressa(R)) 복용 후 발생한 여드름모양 발진 1예A case of acneiform skin eruption associated with ZD1839(Iressa®)

Other Titles
A case of acneiform skin eruption associated with ZD1839(Iressa®)
Authors
김용주황규철유동수오칠환송해준
Issue Date
Apr-2004
Publisher
Korean Dermatological Association
Keywords
Acneiform eruption; ZD1839
Citation
Korean Journal of Dermatology, v.42, no.4, pp 478 - 481
Pages
4
Indexed
SCOPUS
KCI
Journal Title
Korean Journal of Dermatology
Volume
42
Number
4
Start Page
478
End Page
481
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/32256
ISSN
0494-4739
2713-7627
Abstract
Epidermal growth factor (EGF) has an important role in the regulation of the proliferation and differentiation of epidermal keratinocytes, as well as in the survival, angiogenesis and metastasis of various cancer cells. There have been some reports of acneiform skin lesions that occurred in the cancer patients treated with ZD1839(Iressa®), an inhibitor of EGF tyrosine kinase. We report a case of acneiform eruption related to the anticancer drug, ZD1839(Iressa®).
Epidermal growth factor (EGF) has an important role in the regulation of the proliferation and differentiation of epidermal keratinocytes, as well as in the survival, angiogenesis and metastasis of various cancer cells. There have been some reports of acneiform skin lesions that occurred in the cancer patients treated with ZD1839(Iressa®), an inhibitor of EGF tyrosine kinase. We report a case of acneiform eruption related to the anticancer drug, ZD1839(Iressa®).
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Song, Hae Jun
Guro Hospital (Department of Dermatology, Guro Hospital)
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