Analyses of vessel densities and foveal avascular zones using four optical coherence tomography angiography devices
- Authors
- Park, S.Y.; Nam, Ki Tae; Yun, Cheol min; Jang, S.
- Issue Date
- May-2020
- Publisher
- Korean Ophthalmological Society (KOS)
- Keywords
- Foveal avascular zone; Optical coherence tomography angiography; Vessel density
- Citation
- Journal of Korean Ophthalmological Society, v.61, no.5, pp 482 - 490
- Pages
- 9
- Indexed
- SCOPUS
ESCI
KCI
- Journal Title
- Journal of Korean Ophthalmological Society
- Volume
- 61
- Number
- 5
- Start Page
- 482
- End Page
- 490
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/33078
- DOI
- 10.3341/jkos.2020.61.5.482
- ISSN
- 0378-6471
2092-9374
- Abstract
- Purpose: To compare the vessel density (VD) and foveal avascular zone (FAZ) area using four different optical coherence tomography angiography (OCTA) images. Methods: This prospective study analyzed the OCTA images of consecutive healthy subjects using Plex-Elite (Carl Zeiss), DRI OCT-1 Atlantis (Topcon), AngioPlex (Carl Zeiss), and Spectralis OCTA (Heidelberg Engineering). The VD and FAZ areas were calculated using the OCTA images with a 3 x 3 mm2 volume scan pattern centered on the fovea. Results: The VD (%) of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were different using the four devices: Plex-Elite (42.17 ± 2.79, 43.71 ± 2.36), DRI OCT-1 Atlantis (28.70 ± 2.87, 30.27 ± 3.02), AngioPlex (28.32 ± 6.68, 33.33 ± 5.44), and Spectralis OCTA (27.86 ± 4.13, 28.54 ± 3.14), respectively; p < 0.001). The FAZ area (mm2) of the SCP and DCP were different using the four devices: Plex-Elite (0.276 ± 0.097, 0.340 ± 0.100), DRI OCT-1 Atlantis (0.281 ± 0.102, 0.354 ± 0.119), AngioPlex (0.269 ± 0.099, 0.422 ± 0.120), and Spectralis OCTA (0.272 ± 0.079, 0.298 ± 0.106), respectively; p < 0.001). The VD of the SCP and DCP had no significant correlation using the four devices (all, p > 0.05), but the FAZ area had positive correlations using the four devices (all, p < 0.001). Conclusions: The four OCTA devices provided different VD and FAZ areas, so these differences should be considered in analyzing OCTA images. © 2020 The Korean Ophthalmological Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Collections - 2. Clinical Science > Department of Ophthalmology > 1. Journal Articles
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