Medication Adherence of Statin Users after Acute Ischemic Stroke
- Authors
- Chung, Pil-Wook; Yoon, Byung-Woo; Lee, Yeong-Bae; Shin, Byoung-Soo; Kim, Hahn Young; Park, Jae Hyeon; Kim, Byung-Kun; Yoo, Bong-Goo; Shin, Won-chul; Kim, Eung-Gyu; Do, Jin Kuk; Park, Kyung-Pil; Jung, Yohan; Seo, Woo-Keun; Han, Moon-Ku; Kim, Jei; Kim, Yongduk; Bang, Oh Young; Hwang, Yang-Ha; Cha, Jin-Hye; Kim, Young-Joo
- Issue Date
- 2018
- Publisher
- KARGER
- Keywords
- Acute ischemic stroke; Statin adherence; Patient-reported outcomes; Quality of life
- Citation
- EUROPEAN NEUROLOGY, v.80, no.1-2, pp 106 - 114
- Pages
- 9
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- EUROPEAN NEUROLOGY
- Volume
- 80
- Number
- 1-2
- Start Page
- 106
- End Page
- 114
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/34133
- DOI
- 10.1159/000493530
- ISSN
- 0014-3022
1421-9913
- Abstract
- Although statins are established therapy for the secondary prevention of ischemic stroke, factors associated with adherence to statin treatment following ischemic stroke are not well known. To address this, we assessed the 6-month statin adherence using 8-item Morisky Medication Adherence Scale-8 in patients with acute ischemic stroke. Of 991 patients, 65.6% were adherent to statin at 6-month after discharge. Multiple logistic regression analysis showed that patients' awareness of hyperlipidemia (OR 1.62; 95% CI 1.07-2.43), large artery stroke subtype (versus non-large artery stroke, OR 1.79; 95% CI 1.19-2.68), and alcohol drinking habits (OR 1.64; 95% CI 1.06-2.53) were positively associated, while high statin dose (versus low dose, OR 0.6; 95% CI 0.40-0.90) and higher daily number of medication pills (OR 0.93; 95% CI 0.88-0.97) were found to have a negative association with self-reported good adherence to statin medication after acute ischemic stroke. However, stroke severity and diagnosis of hyperlipidemia were not associated with adherence. These results suggest that educational and motivational interventions may enhance statin adherence because modifiable factors were associated with statin adherence.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 2. Clinical Science > Department of Neurology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.