Non-amplification of an allele of the D8S1179 locus due to a point mutation
- Authors
- Han, GR; Song, ES; Hwang, JJ
- Issue Date
- Aug-2001
- Publisher
- SPRINGER-VERLAG
- Keywords
- D8S1179; STR; mutation; multiplex; PCR
- Citation
- INTERNATIONAL JOURNAL OF LEGAL MEDICINE, v.115, no.1, pp 45 - 47
- Pages
- 3
- Indexed
- SCIE
SCOPUS
- Journal Title
- INTERNATIONAL JOURNAL OF LEGAL MEDICINE
- Volume
- 115
- Number
- 1
- Start Page
- 45
- End Page
- 47
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/37235
- DOI
- 10.1007/s004140100213
- ISSN
- 0937-9827
1437-1596
- Abstract
- During a population study of 128 Korean families (626 persons) with the AmpF/STR Profiler Plus PCR amplification system, we found an unusual homozygous genotype at the D8S1179 locus in 4 families. Therefore, a new pair of primers was designed for the D8S1179 locus from GenBank data (GenBank Accession No. G08710) to evaluate the cause. The newly designed primers amplified alleles that were not amplified with the AmpF/STR Profiler Plus PCR amplification system. We sequenced alleles of the family members who had non-amplified alleles and we found a G-to-A transition at the position of the 147th base of the GenBank sequence.
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Collections - 1. Basic Science > Department of Legal Medicine > 1. Journal Articles
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