Cranofacial osteosarcoma: Single institutional experience in Korea
- Authors
- Seungtaek Lim; Jae Kung Rho; Sun Young Rha; Lee, SOOHYEON
- Issue Date
- Jan-2016
- Publisher
- Blackwell Pub. Asia
- Keywords
- head and neck neoplasm; metastasectomy; prognosis; recurrence; sarcoma
- Citation
- Asia-Pacific Journal of Clinical Oncology, v.12, no.1, pp e149 - e153
- Indexed
- SCIE
SCOPUS
- Journal Title
- Asia-Pacific Journal of Clinical Oncology
- Volume
- 12
- Number
- 1
- Start Page
- e149
- End Page
- e153
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/43463
- DOI
- 10.1111/ajco.12072
- ISSN
- 1743-7555
1743-7563
- Abstract
- Introduction: Craniofacial osteosarcoma is a rare disease accounting for only 1% of all head and neck malignancies. Its clinical features and optimal treatments are not yet clearly established.
Methods: We retrospectively analyzed the clinical course of 15 patients with craniofacial osteosarcoma treated in a single institute.
Results: Out of 13 patients who initially underwent primary mass resection, disease recurrence was found in five (36%). Patients with positive surgical margins showed higher recurrence and shorter median recurrence-free and overall survival. Of three patients who had secondary operation after local recurrence, two survived for 44.6 and 64.2 months, respectively. One patient who underwent repeated lung metastasectomy had a disease-free survival of 18.4 months from the first recurrence.
Conclusion: The current study demonstrates that positive surgical margins are important predictive factors for recurrence and overall survival. Salvage surgery for local recurrence and metastasectomy for systemic recurrence might have a positive impact on survival.
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